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LYRM1 Antibody

  • 货号：
    CSB-PA013272LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA013272LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) LYRM1 Polyclonal antibody
  • Uniprot No.：
    O43325
  • 基因名：
    LYRM1
  • 别名：
    1110065L10Rik antibody; 2310004B22Rik antibody; 4930404J24Rik antibody; A211C6.1 antibody; LYR motif containing 1 antibody; LYR motif containing protein 1 antibody; LYR motif-containing protein 1 antibody; LYRM 1 antibody; lyrm1 antibody; LYRM1_HUMAN antibody; OTTHUMP00000162292 antibody; OTTMUSP00000031126 antibody; OTTMUSP00000031127 antibody; OTTMUSP00000031128 antibody; OTTMUSP00000031129 antibody; RGD1563498 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human LYR motif-containing protein 1 protein (1-122AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，LYRM1 Antibody (CSB-PA013272LA01HU)，的标记方式是Non-conjugated。对于LYRM1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA013272LB01HU LYRM1 Antibody, HRP conjugated ELISA
    FITC CSB-PA013272LC01HU LYRM1 Antibody, FITC conjugated
    Biotin CSB-PA013272LD01HU LYRM1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May promote cell proliferation and inhibition of apoptosis of preadipocytes.
  • 基因功能参考文献：
    1. alpha-LA protects 3T3-L1 adipocytes from LYRM1-induced insulin resistance partially via its capacity to restore mitochondrial function and/or increase phosphorylation of IRS-1 and Akt. PMID: 22820890
    2. overexpression of LYRM1 caused mitochondrial dysfunction in adipocytes, which might be responsible for the development of LYRM1-induced insulin resistance PMID: 20826099
    3. Data suggest that LYRM1 might have the potential to modulate cell growth, apoptosis, and heart development. PMID: 20938407
    4. By increasing cell proliferation and lowering the rate of apoptosis, LYRM1 has the potential to modulate the size of the preadipocyte pool and influence adipose tissue homeostasis PMID: 19022914
  • 相关疾病：
    When overexpressed, may be involved in obesity-associated insulin resistance, possibly by causing mitochondrial dysfunction in adipocytes.
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Complex I LYR family
  • 组织特异性：
    High levels in adipose tissue.
  • 数据库链接：

    HGNC: 25074

    OMIM: 614709

    KEGG: hsa:57149

    STRING: 9606.ENSP00000219168

    UniGene: Hs.745012