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TRAM2 Antibody

  • 货号：
    CSB-PA624011LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA624011LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA624011LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TRAM2 Polyclonal antibody
  • Uniprot No.：
    Q15035
  • 基因名：
    TRAM2
  • 别名：
    TRAM2; KIAA0057; Translocating chain-associated membrane protein 2
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Translocating chain-associated membrane protein 2 protein (316-370AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TRAM2 Antibody (CSB-PA624011LA01HU)，的标记方式是Non-conjugated。对于TRAM2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA624011LB01HU TRAM2 Antibody, HRP conjugated ELISA
    FITC CSB-PA624011LC01HU TRAM2 Antibody, FITC conjugated
    Biotin CSB-PA624011LD01HU TRAM2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).
  • 基因功能参考文献：
    1. TRAM2, as a part of the translocon, is required for the biosynthesis of type I collagen by coupling the activity of SERCA2b with the activity of the translocon PMID: 14749390
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    TRAM family
  • 数据库链接：

    HGNC: 16855

    OMIM: 608485

    KEGG: hsa:9697

    STRING: 9606.ENSP00000182527

    UniGene: Hs.520182