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  4. Recombinant Drosophila melanogaster Probable phosphomannomutase (CG10688)

Recombinant Drosophila melanogaster Probable phosphomannomutase (CG10688)

  • 中文名称：
    Recombinant Drosophila melanogaster Probable phosphomannomutase(CG10688),Yeast
  • 货号：
    CSB-YP893804DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Probable phosphomannomutase(CG10688),Yeast
  • 货号：
    CSB-EP893804DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Probable phosphomannomutase(CG10688),Yeast
  • 货号：
    CSB-EP893804DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Probable phosphomannomutase(CG10688),Yeast
  • 货号：
    CSB-BP893804DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Drosophila melanogaster Probable phosphomannomutase(CG10688),Yeast
  • 货号：
    CSB-MP893804DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CG10688
  • Uniprot No.：
  • 别名：
    CG10688; Probable phosphomannomutase; PMM; EC 5.4.2.8
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-254
  • 氨基酸序列
    MTTAALKRDE ILLLFDVDGT LTMPRSVVTP EFEEFFYSRV KPRATIGIVG GSDLEKMFEQ LNGRKILNEF DFIFPENGLV QIEGGKEVGK QNIIMHLGEE TVKRFINFVL RYLSELDVPI KRGTFIEFRN GMMNVCPIGR QCTREERNMF AEYDIEHKVR EKMIKDLKQE FADVDLTYSI GGQISFDVFP HGWDKTYCLR HIEAHYKFKE IHFFGDKTEP GGNDYEIYSD PRTISHRVYT PKDTQRILTE ILEL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. Required for maintaining N-linked glycoprotein glycosylation at the neuromuscular junction (NMJ) synaptomatrix, and thus acts in multiple pathways that prevent NMJ structural overgrowth, restrict synaptic bouton differentiation, and limit NMJ neurotransmission strength, in order to maintain viability, coordinate movement, and in adults ensure correct wing positioning. Acts in the NMJ trans-synaptic Wg pathway via glycosylation of synaptic Mmp2 which enables dlp/wg signaling during development.
  • 基因功能参考文献：
    1. CRISPR-generated pmm2-null Drosophila mutants display severely disrupted glycosylation and early lethality. PMID: 26940433
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Eukaryotic PMM family
  • 数据库链接：

    KEGG: dme:Dmel_CG10688

    STRING: 7227.FBpp0075693

    UniGene: Dm.23285