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  4. Recombinant Mouse Spermatogenic leucine zipper protein 1 (Spz1)

Recombinant Mouse Spermatogenic leucine zipper protein 1 (Spz1)

  • 中文名称：
    小鼠Spz1重组蛋白
  • 货号：
    CSB-YP858159MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Spz1重组蛋白
  • 货号：
    CSB-EP858159MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Spz1重组蛋白
  • 货号：
    CSB-EP858159MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Spz1重组蛋白
  • 货号：
    CSB-BP858159MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Spz1重组蛋白
  • 货号：
    CSB-MP858159MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Spz1
  • Uniprot No.：
  • 别名：
    Spz1; Spermatogenic leucine zipper protein 1; BHLH-Zip transcription factor SPZ1; Spermatogenic Zip 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-378
  • 氨基酸序列
    MSDTDNSAEM PARCPSPNPA PGAKQEPPNS GITISLLEIG SLPTVCYHSF PPPKNSICPV EKRGRVQKFS NLLKDVKDVL KNIAGVEEKS TVGEPFDDAY IPEDLSELNV RGVEKKNKIR FKDDLFIHFD PEREQNTMKQ MLLKNQSAKN MVPKFARDLC NAEETRGFDG MLLSVKRPRN GSLHLRGEYR KLRNNMEQLL QEADHWSKQH NELSELMRSY QECQNETQET TDKDRACLQN QPNNGLSTKQ KLEEQVKKLS HDTHALHLIA ALLENECQVL QQRVDILKDF HLHEAGLGHE KPLQMSCEQD KKCPKLAEAD KTDAFKHTTR ATEGTIRKPK ILRSPDVCFT KKARNNRFNA RVAKKSLVGK RRTVSSFR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. Directly binds to a guanine-rich region of the PCNA promoter and up-regulates its expression which in turn induces cell transformation and tumor formation. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis.
  • 基因功能参考文献：
    1. Spz1 has a regulatory role during spermatogenesis. PMID: 14980513
    2. the interaction between Spz1 and PP1cgamma2 may be required for proper regulation of spermatogenesis and fertility in males PMID: 15226296
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 组织特异性：
    Expressed specifically in the testis and epidydimis. In the testis expressed in both germ cells and somatic cells (Sertoli and Leydig cells). Expressed in several tumor cell lines.
  • 数据库链接：

    KEGG: mmu:79401

    STRING: 10090.ENSMUSP00000054083

    UniGene: Mm.23520