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  4. Recombinant Mouse TSC22 domain family protein 4 (Tsc22d4)

Recombinant Mouse TSC22 domain family protein 4 (Tsc22d4)

  • 中文名称：
    小鼠Tsc22d4重组蛋白
  • 货号：
    CSB-EP887652MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Tsc22d4重组蛋白
  • 货号：
    CSB-EP887652MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Tsc22d4重组蛋白
  • 货号：
    CSB-BP887652MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Tsc22d4重组蛋白
  • 货号：
    CSB-MP887652MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
    Name:Tsc22d4 Synonyms:Tilz2
  • Uniprot No.：
  • 别名：
    Tsc22d4; Thg1pit; Tilz2; TSC22 domain family protein 4; TSC22-related-inducible leucine zipper protein 2; Thg-1pit
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-387
  • 氨基酸序列
    MSGGKKKSSF QITSVTTDYE GPGSPGASDS PVPPALAGPP PRLPNGDPNP DPGGRGTPRN GSPPPGAPAS RFRVVKLPQG LGEPYRRGRW TCVDVYERDL EPPSFGRLLE GIRGASGGTG GRSLDSRLEL ASLGISTPIP QPGLSQGPTS WLRPPPTSPG PQARSFTGGL GQLAGPGKAK VETPPLSASP PQQRPPGPGT GDSAQTLPSL RVEVESGGSA AATPPLSRRR DGAVRLRMEL VAPAETGKVP PTDSRPNSPA LYFDASLVHK SPDPFGAAAA QSLSLARSML AISGHLDSDD DSGSGSLVGI DNKIEQAMDL VKSHLMFAVR EEVEVLKEQI RDLAERNAAL EQENGLLRAL ASPEQLAQLP SSGLPRLGPS APNGPSI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional repressor.
  • 基因功能参考文献：
    1. Liver-specific ablation of TSC22D4 triggered hypertriglyceridemia through the induction of hepatic VLDL secretion. PMID: 23307490
    2. In vitro TSC22D4 silencing with small interfering (si)RNAs blocks granule cell differentiation and inhibits neurite elongation in neuroblastoma cells, pinpointing the relevance of this protein to granule cell differentiation. PMID: 20878296
    3. Thg-1 pit is relevant to specification, proliferation/migration, differentiation, and mature function of granule/interneuron cells in different brain districts [Thg-1 pit] PMID: 15895388
    4. TSC22D4 is stably upregulated by hyperosmolality in mIMCD3 cells and increased in renal papilla compared with cortex. PMID: 17147695
    5. TSC-22 is a potential tumor suppressor that is upregulated by Flt3-D835V but not Flt3-ITD PMID: 17690703
    6. Results suggest that THG-1pit is involved in the induction of granule neuron apoptosis. PMID: 19084601

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    TSC-22/Dip/Bun family
  • 数据库链接：

    KEGG: mmu:78829

    STRING: 10090.ENSMUSP00000098108

    UniGene: Mm.286399