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  4. Recombinant Protein C (P/V/C)

Recombinant Protein C (P/V/C)

  • 货号：
    CSB-YP860354NDT
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP860354NDT
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP860354NDT-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP860354NDT
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP860354NDT
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    P/V/C
  • Uniprot No.：
  • 别名：
    P/V/CProtein C
  • 种属：
    Nipah virus
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-166
  • 氨基酸序列
    MMASILLTLF RRTKKKYRRH TDDQVFNNPA SKIKQKPGKI FCSAPVENLN KLRGECLRMM EMLKEETWRI YPVLLPQMEL LERECRTPVT GQKVQMTYNW TQWLQTLYTM IMEENVPDMD LLQALREGGV ITHQEQTMGM YVLYLMQRCC PMLPKLQFLK KIGKLI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May counteract the cellular interferon antiviral system.
  • 基因功能参考文献：
    1. we find that the virus C protein, which was previously investigated for its role in antagonism of innate immunity, recruits the ESCRT pathway to promote efficient virus release. PMID: 27203423
    2. V protein is the major determinant of pathogenesis. W protein modulates the inflammatory host immune response in a manner that determines the disease course. PMID: 26105519
    3. Using both biochemical and biophysical approaches, s show that Nipah virus phosphoprotein multimerization domain forms a highly stable and elongated coiled-coil trimer. PMID: 24074578
    4. Multiple elements encoded by the P gene have both distinct and overlapping roles in modulating virus replication as well as in limiting expression of antiviral cytokines. PMID: 23094089
    5. Nonstructural Nipah virus C protein regulates both the early host proinflammatory response and viral virulence PMID: 22837207
    6. study describes a mutant of the NiV V protein, referred to as V(AAHL), that is unable to antagonize interferon signalling and demonstrates that a single amino acid substitution is responsible for its inactivity PMID: 17098981
    7. By use of specific antibodies, the expression of the V, W, and C proteins in NiV-infected cells has now been confirmed. PMID: 19211754
    8. P protein sequesters STAT1 in the nucleus and prevents its activation. PMID: 19515782

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