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Bovine Angiopoietin-1(ANGPT1) ELISA kit

  • 中文名称:
    牛血管生成素1(ANGPT1)酶联免疫试剂盒
  • 货号:
    CSB-EL001706BO
  • 规格:
    96T/48T
  • 价格:
    ¥4200/¥3000
  • 其他:

产品详情

  • 产品描述:
        ANGPT1 (Angiopoietin 1)是一种蛋白质,参与调节血管生成和维持血管的稳定性。它可以通过与其受体TIE2结合来促进血管内皮细胞的成熟和稳定性。
     
        j9九游会登录入口首页生物所提供的Bovine Angiopoietin-1(ANGPT1) ELISA kit属于ELISA检测试剂盒,采用双抗夹心法定量检测牛血清、血浆、组织匀浆样本中的ANGPT1,其灵敏度为1.384 ng/mL,检测范围为12.5 ng/mL-800 ng/mL。
     
  • 别名:
    ANGPT1 ELISA kit; ANG1Angiopoietin-1 ELISA kit; ANG-1 ELISA kit
  • 缩写:
  • Uniprot No.:
  • 种属:
    Bos taurus (Bovine)
  • 样本类型:
    serum, plasma, tissue homogenates
  • 检测范围:
    12.5 ng/mL-800 ng/mL
  • 灵敏度:
    1.384 ng/mL
  • 反应时间:
    1-5h
  • 样本体积:
    50-100ul
  • 检测波长:
    450 nm
  • 研究领域:
    Cardiovascular
  • 测定原理:
    quantitative
  • 测定方法:
    Sandwich
  • 数据处理:
  • 货期:
    3-5 working days

产品评价

靶点详情

  • 最新研究进展:
        血管生成素1(ANGPT1)是一种血管生成素家族成员,与血管生成、血管增生和血管通透性调节有关。最新的研究表明,ANGPT1在心血管系统、免疫系统、肿瘤学等领域中都具有重要作用,并且可能是潜在的治疗靶点。研究人员正在探索ANGPT1与其相关的信号通路,以便更好地了解其生物学功能和作为治疗靶点的潜力。
  • 功能:
    Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.
  • 基因功能参考文献:
    1. Angiopoietin-1 receptor Tie2 distinguishes multipotent differentiation capability in bovine coccygeal nucleus pulposus cells. PMID: 27216150
    2. ANPT-1 becomes predominant in the follicle producing high levels of E(2), indicating the possible switch-over from ANPT-2 (antagonist) to ANPT-1 (agonist). PMID: 15329480
    3. inhibition of NO production by Ang-1, via phosphorylation of eNOS on Thr(497) by PKC zeta, is responsible, at least in part, for inhibition of VEGF-stimulated endothelial permeability by Ang-1. PMID: 19564638
  • 亚细胞定位:
    Secreted.
  • 数据库链接:

    KEGG: bta:282140

    UniGene: Bt.91353