Bovine Angiopoietin-1(ANGPT1) ELISA kit
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中文名称:牛血管生成素1(ANGPT1)酶联免疫试剂盒
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货号:CSB-EL001706BO
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规格:96T/48T
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价格:¥4200/¥3000
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其他:
产品详情
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产品描述:ANGPT1 (Angiopoietin 1)是一种蛋白质,参与调节血管生成和维持血管的稳定性。它可以通过与其受体TIE2结合来促进血管内皮细胞的成熟和稳定性。j9九游会登录入口首页生物所提供的Bovine Angiopoietin-1(ANGPT1) ELISA kit属于ELISA检测试剂盒,采用双抗夹心法定量检测牛血清、血浆、组织匀浆样本中的ANGPT1,其灵敏度为1.384 ng/mL,检测范围为12.5 ng/mL-800 ng/mL。
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别名:ANGPT1 ELISA kit; ANG1Angiopoietin-1 ELISA kit; ANG-1 ELISA kit
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缩写:
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Uniprot No.:
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种属:Bos taurus (Bovine)
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样本类型:serum, plasma, tissue homogenates
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检测范围:12.5 ng/mL-800 ng/mL
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灵敏度:1.384 ng/mL
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Cardiovascular
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测定原理:quantitative
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测定方法:Sandwich
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数据处理:
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货期:3-5 working days
相关产品
靶点详情
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最新研究进展:血管生成素1(ANGPT1)是一种血管生成素家族成员,与血管生成、血管增生和血管通透性调节有关。最新的研究表明,ANGPT1在心血管系统、免疫系统、肿瘤学等领域中都具有重要作用,并且可能是潜在的治疗靶点。研究人员正在探索ANGPT1与其相关的信号通路,以便更好地了解其生物学功能和作为治疗靶点的潜力。
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功能:Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.
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基因功能参考文献:
- Angiopoietin-1 receptor Tie2 distinguishes multipotent differentiation capability in bovine coccygeal nucleus pulposus cells. PMID: 27216150
- ANPT-1 becomes predominant in the follicle producing high levels of E(2), indicating the possible switch-over from ANPT-2 (antagonist) to ANPT-1 (agonist). PMID: 15329480
- inhibition of NO production by Ang-1, via phosphorylation of eNOS on Thr(497) by PKC zeta, is responsible, at least in part, for inhibition of VEGF-stimulated endothelial permeability by Ang-1. PMID: 19564638
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亚细胞定位:Secreted.
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数据库链接:
KEGG: bta:282140
UniGene: Bt.91353
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