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  4. Rabbit C-Reactive Protein,CRP ELISA Kit

Rabbit C-Reactive Protein,CRP ELISA Kit

  • 中文名称：
    兔子C反应蛋白(CRP)酶联免疫试剂盒
  • 货号：
    CSB-E06847Rb
  • 规格：
    96T/48T
  • 价格：
    ￥4200/￥3000
  • 其他：

产品详情

  • 产品描述：

    This Rabbit CRP ELISA Kit was designed for the quantitative measurement of Rabbit CRP protein in serum, plasma. It is a Sandwich ELISA kit, its detection range is 7.8 pg/mL-2000 pg/mL and the sensitivity is 2 pg/mL.

  • 别名：
    CRP ELISA kit; PTX1C-reactive protein ELISA kit
  • 缩写：
  • Uniprot No.：
  • 种属：
    Oryctolagus cuniculus (Rabbit)
  • 样本类型：
    serum, plasma
  • 检测范围：
    7.8 pg/mL-2000 pg/mL
  • 灵敏度：
    2 pg/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Immunology
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%      
    Three samples of known concentration were tested twenty times on one plate to assess.  
    Inter-assay Precision (Precision between assays): CV%<10%      
    Three samples of known concentration were tested in twenty assays to assess.    
                 
  • 线性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of rabbit CRP in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　 Sample Serum(n=4)  
    1:1000 Average % 96  
    Range % 90-102  
    1:2000 Average % 91  
    Range % 82-96  
    1:4000 Average % 90  
    Range % 85-98  
    1:8000 Average % 94  
    Range % 83-98  
  • 回收率：
    The recovery of rabbit CRP spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample Type Average % Recovery Range  
    Serum (n=5) 97 90-104  
    EDTA plasma (n=4) 91 85-96  
                 
                 
  • 标准曲线：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/ml OD1 OD2 Average    
    2000 0.196 0.198 0.197    
    500 0.353 0.371 0.362    
    125 0.669 0.651 0.660    
    31.3 1.084 1.035 1.060    
    7.8 2.018 1.974 1.996    
    0 2.913 3.122 3.018    
  • 数据处理：
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 功能：
    Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
  • 基因功能参考文献：
    1. Rabbit CRP acute-phase system binds phosphocholine and phosphoethanolamine. PMID: 23600950
    2. IL-6 augments mechanical strain-induced CRP synthesis in vessels via the stretch-activated channel-NF-kappaB pathway. PMID: 23257175
    3. CRP antagonism of eNOS is mediated by coupling of FcgammaRI to FcgammaRIIB by Src kinase and activation of inositol 5'-phosphatase 1, and consistent with this mechanism, both FcgammaRI and FcgammaRIIB are required for CRP to blunt endothelial repair in vivo. PMID: 21940940
    4. Metformin attenuated the progression of aortic atherosclerosis via down-regulation of serum C-reactive protein. PMID: 20108078
    5. During abdominal aortic aneurysm formation, increased serum hsCRP levels derive from aneurysmal arteries with degenerating elastic lamina. PMID: 19502992

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Pentraxin family
  • 组织特异性：
    Found in plasma.
  • 数据库链接：