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中文名称:大鼠皮质酮/肾上腺酮(CORT)酶联免疫试剂盒
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货号:CSB-E07014r
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规格:96T/48T
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价格:¥3900/¥2500
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其他:
产品详情
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产品描述:CORT(皮质酮)是一种内源性激素,由肾上腺分泌,与应激、代谢、免疫调节等生理过程密切相关。
j9九游会登录入口首页生物所提供的Rat Corticosterone,CORT ELISA Kit属于ELISA检测试剂盒,采用竞争法定量检测大鼠血清、血浆、组织匀浆样本中的CORT,其灵敏度为0.1 ng/mL,检测范围为0.2 ng/mL-40 ng/mL。 -
别名:N/A
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缩写:CORT
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种属:Rattus norvegicus (Rat)
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样本类型:serum, plasma, tissue homogenates
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检测范围:0.2 ng/mL-40 ng/mL
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灵敏度:0.1 ng/mL
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Signal Transduction
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测定原理:quantitative
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测定方法:Competitive
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精密度:
Intra-assay Precision (Precision within an assay): CV%<15% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<15% Three samples of known concentration were tested in twenty assays to assess. -
线性度:
To assess the linearity of the assay, samples were spiked with high concentrations of rat CORT in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. Sample Serum(n=4) 1:1 Average % 84 Range % 80-91 1:2 Average % 90 Range % 85-95 1:4 Average % 97 Range % 92-103 1:8 Average % 105 Range % 100-112 -
回收率:
The recovery of rat CORT spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. Sample Type Average % Recovery Range Serum (n=5) 95 89-99 EDTA plasma (n=4) 92 88-97 -
标准曲线:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. ng/ml OD1 OD2 Average 40 0.138 0.132 0.135 10 0.239 0.258 0.249 3.2 0.504 0.509 0.507 0.8 0.939 1.009 0.974 0.2 1.419 1.424 1.422 0 2.154 2.159 2.157 -
数据处理:
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货期:3-5 working days
引用文献
- Increase of circulating cfDNA by chronic training or overtraining in human and rat and its possible mechanisms LJ Yin,Science & Sports,2023
- Association analysis of gut microbiota-metabolites-neuroendocrine changes in male rats acute exposure to simulated altitude of 5500 m J Wang,Scientific reports,2023
- Can Resveratrol Influence the Activity of 11β-Hydroxysteroid Dehydrogenase Type 1? A Combined In Silico and In Vivo Study J Novak,Pharmaceuticals,2023
- Paradoxical Anxiety Level Reduction in Animal Chronic Stress: A Unique Role of Hippocampus Neurobiology Vadim Tseilikman,International Journal of Molecular Sciences,2022
- Circ_0000181 regulates miR-667-5p/NLRC4 axis to promote pyroptosis progression in diabetic nephropathy Y Li,Scientific reports,2022
- The extent of involvement of ouabain, hippocampal expression of Na+/K+-ATPase, and corticosterone/melatonin receptors ratio in modifying stress-induced behavior differs according to the stressor in context S Abdelmissih,Brazilian journal of medical and biological research,2022
- Total Saikosaponins Attenuates Depression-Like Behaviors Induced by Chronic Unpredictable Mild Stress in Rats by Regulating the PI3K/AKT/NF-κB … Z Zhou,Evidence-Based Complementary and Alternative Medicine,2022
- The Link between Activities of Hepatic 11beta-Hydroxysteroid Dehydrogenase-1 and Monoamine Oxidase-A in the Brain Following Repeated Predator Stress: Focus on Heightened Anxiety V Tseilikman,International journal of molecular sciences,2022
- Jie-Yu-He-Huan Capsule Ameliorates Anxiety-Like Behaviours in Rats Exposed to Chronic Restraint Stress via the cAMP/PKA/CREB/BDNF Signalling Pathway Xiwen Geng,Oxidative Medicine and Cellular Longevity,2021
- Neurotoxic Effect of Fipronil in Male Wistar Rats: Ameliorative Effect of L-Arginine and L-Carnitine YK Mahmoud,Biology,2021
- PET neuroimaging reveals upregulation of dopamine D2 receptor contributes to amygdaloid dysfunction in rat acute restraint stress model Z Yan,Biochemical and Biophysical Research Communications,2021
- Norepinephrine in the dentate gyrus is involved in spatial learning and memory alteration induced by chronic restraint stress in aged rats FX Wang,Neuroreport,2020
- Effect of Light-Dark Cycle Misalignment on the Hypothalamic-Pituitary-Gonadal Axis, Testicular Oxidative Stress, and Expression of Clock Genes in Adult Male Rats A Moustafa,International journal of endocrinology,2020
- Changes in nitric oxide, carbon monoxide, hydrogen sulfide and male reproductive hormones in response to chronic restraint stress in rats A Moustafa,Free Radical Biology and Medicine,2020
- Swim therapy-induced tissue specific metabolic responses in male rats A Moustafa,Life Sciences,2020
- MODULATION OF DEPRESSION-LIKE BEHAVIOR BY A COMBINATION WITH VITAMIN D3 AND 17Β-ESTRADIOL IN MIDDLE-AGED OVARIECTOMIZED RATS SUBJECTED TO CHRONIC MILD STRESS V Mironova,Opera Medica et Physiologica,2020
- The Involvement of Notch1 Signaling Pathway in Mid-aged Female Rats under Chronic Restraint Stress J Shen,Neuroscience Letters,2020
- Saponin extract of Baihe-Zhimu Tang ameliorates depression in chronic mild stress rats D Jia,Journal of Functional Foods,2020
- Hyperfunction of the stress response system and novelty┸\induced hyperactivity correlate with enhanced cocaine┸\induced conditioned place preference in NCAM … B K盲hler,Addict Biol,2020
- Increased Oxidative Damage Contributes to Mitochondrial Dysfunction in Muscle of Depressed Rats Induced by Chronic Mild Stress Probably Mediated by SIRT3 … Q Xiao,ANIMAL AND HUMAN PHYSIOLOGY,2020
- Vitamin D3 attenuates anxiety-like behavior in long-term ovariectomized rats with unpredictable mild stress BARANENKO D,BIOCELL,2019
- Synergic action of Vitamin D3 and 17β-estradiol on behavioral impairments induced by unpredictable mild stress in the adult ovariectomized female rats Fedotova J, et al,Biorxiv,2019
- Mechanisms of Stress-Induced Spermatogenesis Impairment in Male Rats Following Unpredictable Chronic Mild Stress (uCMS) Zou P, et al,International Journal of Molecular Sciences,2019
- Metabolomic signatures and microbial community profiling of depressive rat model induced by adrenocorticotrophic hormone Song J, et al,Journal of Translational Medicine,2019
- Acute restraint stress alters food-foraging behavior in rats: Taking the easier Way while suffered Tu BX,Brain Research Bulletin,2019
- Chronic paradoxical sleep deprivation-induced depression Ma W, et al,Life Sciences,2019
- Changes in Secretory Activity of Adrenal Zona Fasciculata Cells in Pubertal Rats Exposed to Low Doses of DDT in Different Periods of Ontogeny Yaglova NV, et al,Bulletin of experimental biology and medicine,2018
- Social defeat stress before pregnancy induces depressive-like behaviours and cognitive deficits in adult male offspring: correlation with neurobiological changes Wei S.et al,BMC Neuroscience,2018
- Transplantation of bone marrow mesenchymal stem cells reduces GluR1 expression in the hippocampus and amygdala and affects secretion of stress-related hormones in rats with spinal cord injuries: a potential anti-chronic stress mechanism Jia-Jia Sun.et al,INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,2018
- Perfluorooctane sulfonate (PFOS) can alter the hypothalamic?pituitary?adrenal (HPA) axis activity by modifying CRF1 and glucocorticoid receptors R. Salgado.et al,Toxicology Letters,2018
- Antidepressant-like effect of lipid extract of Channa striatus in postpartum model of depression in rats Abdul Shukkoor MS.et al,Evid Based Complement Alternat Med,2016
- Acupuncture alters pro-inflammatory cytokines in the plasma of maternally separated rat pups Wang Z.et al,Chin J Integr Med. ,2017
- Role of early environmental enrichment on the social dominance tube test at adulthood in the rat Cao WY.et al,Psychopharmacology (Berl).,2017
- Protective effects of carnosol against oxidative stress induced brain damage by chronic stress in rats Samarghandian S.et al,BMC Complement Altern Med.,2017
- Curcumin reverses the depressive-like behavior and insulin resistance induced by chronic mild stress Shen JD.et al,Metab Brain Dis.,2017
- Exogenous hydrogen sulfide eliminates spatial memory retrieval impairment and hippocampal CA1 LTD enhancement caused by acute stress via promoting glutamate uptake He J.et al,Neuroscience,2017
- THERAPEUTICS FOR THE INDUCTION OF ENDOGENOUS STEROIDOGENESIS AND METHODS ASSOCIATED WITH THEIR IDENTIFICATION Papadopoulos V.et al, U.S. Patent ,2016
- Insulin-like growth factor 2 mitigates depressive behavior in a rat model of chronic stress. Luo YW.et al,Neuropharmacology.,2015
- Protective Effects of Carvacrol against Oxidative Stress Induced by Chronic Stress in Rat's Brain, Liver, and Kidney Saeed Samarghandian. et al,Biochemistry Research International,2016
- Effect of chrysin on nociception in formalin test and serum levels of noradrenalin and corticosterone in rats Gheibi N et al,Basic Clin Neurosci,2015
- Regulation of corticosterone secretion is modified by PFOS exposure at different levels of the hypothalamic-pituitary-adrenal axis in adult male rats Pereiro N et al,Toxicol Lett,2014
- Orcinol glucoside produces antidepressant effects by blocking the behavioural and neuronal deficits caused by chronic stress Ge JF et al,Eur Neuropsychopharmacol,2013
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靶点详情
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最新研究进展:CORT是一种重要的激素,可以影响多种生理过程,如免疫和应激反应。最近的研究表明,CORT可以通过影响免疫细胞的活动来调节免疫反应。例如,在炎症过程中,CORT可以抑制炎症介质的产生,从而缓解炎症反应。此外,CORT也被认为是抑制免疫系统过度激活的重要因素之一。最近的研究还表明,CORT可能在多种神经系统疾病中具有治疗潜力,例如抑郁症和焦虑症等。
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