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Rat Epithelial neutrophil activating peptide 78,ENA-78 ELISA Kit

  • 中文名称:
    大鼠上皮中性粒细胞活化肽78(ENA-78/CXCL5)酶联免疫试剂盒
  • 货号:
    CSB-E08179r
  • 规格:
    96T/48T
  • 价格:
    ¥3600/¥2500
  • 其他:

产品详情

  • 产品描述:
        CXCL5(细胞因子C-X-C motif ligand 5)是一种由多种细胞产生的趋化因子,参与了许多生物学过程,如免疫应答、炎症反应和肿瘤发生等。CXCL5与癌症发展相关,因此被认为是一种潜在的治疗靶点。
        j9九游会登录入口首页生物所提供的Rat Epithelial neutrophil activating peptide 78,ENA-78 ELISA Kit属于ELISA检测试剂盒,采用双抗夹心法定量检测大鼠血清、血浆、组织匀浆样本中的CXCL5,其灵敏度为0.078 ng/mL,检测范围为0.312 ng/mL-20 ng/mL。
     
  • 别名:
    Cxcl5 ELISA Kit; Scyb5C-X-C motif chemokine 5 ELISA Kit; Cytokine LIX ELISA Kit; Small-inducible cytokine B5 ELISA Kit
  • 缩写:
  • Uniprot No.:
  • 种属:
    Rattus norvegicus (Rat)
  • 样本类型:
    serum, plasma, tissue homogenates
  • 检测范围:
    0.312 ng/mL-20 ng/mL
  • 灵敏度:
    0.078 ng/mL
  • 反应时间:
    1-5h
  • 样本体积:
    50-100ul
  • 检测波长:
    450 nm
  • 研究领域:
    Immunology
  • 测定原理:
    quantitative
  • 测定方法:
    Sandwich
  • 数据处理:
  • 货期:
    3-5 working days

产品评价

靶点详情

  • 最新研究进展:
    CXCL5,也称为ENA-78,是一种重要的趋化因子蛋白,可诱导中性粒细胞和其他白细胞向感染或炎症部位迁移。最近的研究表明,CXCL5在多种肿瘤中的表达与恶性程度和预后密切相关,并且可作为潜在的治疗靶点。
  • 功能:
    May participate in the recruitment of inflammatory cells by injured or infected tissue.
  • 基因功能参考文献:
    1. CRH suppressed CXCL5 production in glia via CRHR1 in the hippocampus of male rats. PMID: 29126185
    2. up-regulation of spinal CXCL5 and CXCR2 is involved in neuropathic pain after nerve injury, through regulating GSK-3beta activity in rats. PMID: 27717828
    3. Analysis of mitogen-activated protein kinases (MAPK) and glycogen synthase kinase (GSK3) pathways showed that they are involved in mechanisms of neuronal apoptosis in response to the depletion of CXCL5/LIX signaling. PMID: 22034072
    4. Data demonstrate that the chemokine CXCL5 is a peripheral mediator of UVB-induced inflammatory pain, likely in humans as well as rats. PMID: 21734176
    5. Disrupted expression of CXCL5 in colorectal cancer is associated with rapid tumor formation in rats and poor prognosis in patients. PMID: 18413816

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  • 亚细胞定位:
    Secreted.
  • 蛋白家族:
    Intercrine alpha (chemokine CxC) family
  • 数据库链接: