Rat Interleukin 1β,IL-1β ELISA Kit
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中文名称:大鼠白介素1β (IL-1β)酶联免疫试剂盒
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货号:CSB-E08055r
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规格:96T/48T
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价格:¥3200/¥2500
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其他:
产品详情
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产品描述:IL1B (白细胞介素-1β,Interleukin-1β) 是由许多不同类型的细胞产生的促炎症细胞因子,包括单核细胞、巨噬细胞、树突状细胞、T细胞和B细胞等。IL1B 参与了许多生理和病理过程,包括炎症、感染、肿瘤、自身免疫疾病等。j9九游会登录入口首页生物所提供的Rat Interleukin 1β,IL-1β ELISA Kit属于ELISA检测试剂盒,采用双抗夹心法定量检测大鼠血清、血浆、组织匀浆样本中的IL1B,其灵敏度为0.039 ng/ml,检测范围为0.156 ng/ml-10 ng/ml。
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别名:Il1bInterleukin-1 beta ELISA kit; IL-1 beta ELISA kit
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缩写:
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Uniprot No.:
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种属:Rattus norvegicus (Rat)
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样本类型:serum, plasma, tissue homogenates.
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检测范围:0.156 ng/ml-10 ng/ml.
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灵敏度:0.039 ng/ml.
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Immunology
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测定原理:quantitative
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测定方法:Sandwich
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数据处理:
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货期:3-5 working days
引用文献
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问答及客户评论
■ 客户评论
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Tested application: ELISA
Test sample: Tissue homogenate (brain)
Species: Rat
Review: The test is carried out in a simple way, the samples in repetitions come out very repetitive, only small differences in groups. The samples were not diluted, the results approximated to half the standard curve. The samples were converted to the amount of protein calculated using the BCA method.
靶点详情
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最新研究进展:IL-1β是一种由单核细胞和巨噬细胞产生的细胞因子,能够介导炎症和免疫反应。最新研究发现,IL-1β参与多种疾病的发生和发展,包括肿瘤、自身免疫病和神经退行性疾病等。目前已有研究在探索针对IL-1β的治疗方案,如使用IL-1β抑制剂等。此外,一些研究还发现IL-1β的多态性可能与特定疾病的风险相关。
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功能:Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.
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亚细胞定位:Cytoplasm, cytosol. Lysosome. Secreted, extracellular exosome. Secreted.
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蛋白家族:IL-1 family
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数据库链接:
STRING: 10116.ENSRNOP00000006308
UniGene: Rn.9869
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