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GPR32 Antibody

  • 货号:
    CSB-PA008928
  • 规格:
    ¥880
  • 其他:

产品详情

  • Uniprot No.:
    O75388
  • 基因名:
  • 别名:
    GPR32; Probable G-protein coupled receptor 32
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human GPR32.
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated
  • 抗体亚型:
    IgG
  • 纯化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式:
    Liquid
  • 应用范围:
    WB, IF, ELISA
  • 推荐稀释比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Orphan receptor.
  • 基因功能参考文献:
    1. Data suggest that resolvin D1/RVDR1 signaling (1) promotes epithelial wound repair, (2) inhibits TGFB-induced epithelial-mesenchymal transition in type II alveolar cells, (3) inhibits fibroproliferation and apoptosis, (4) reduces effects of TGFB on primary lung fibroblast collagen production, and (5) inhibits myofibroblast differentiation. (TGFB = transforming growth factor beta) PMID: 29083412
    2. Our findings indicate that chitotriosidase and S10012A are useful in diagnosis and detection of subclinical inflammation and/or assessment of disease activity in FMF patients. PMID: 26339162
    3. Resolvin D1 attenuates the viral mimic-induced inflammatory signaling in human airway epithelial cells via TAK1. PMID: 25320283
    4. Results suggest that resolvin D1 inhibited TGF-beta1-induced EMT via ALX/FPR2 and GPR32 by reducing the expression of ZEB1. PMID: 24120851
    5. results indicate that RvD1 specifically interacts with both ALX and GPR32 on phagocytes. PMID: 20080636

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  • 亚细胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 数据库链接:

    HGNC: 4487

    OMIM: 603195

    KEGG: hsa:2854

    STRING: 9606.ENSP00000270590

    UniGene: Hs.515555