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PPP2CB Antibody

  • 货号：
    CSB-PA234947
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA234947(PPP2CB Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA234947(PPP2CB Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    P62714
  • 基因名：
  • 别名：
    PP2A beta antibody; PP2A-beta antibody; PP2AB_HUMAN antibody; PP2Abeta antibody; PP2CB antibody; Ppp2cb antibody; Protein phosphatase 2 (formerly 2A); catalytic subunit; beta isoform antibody; Protein phosphatase 2 catalytic subunit beta isozyme antibody; Protein phosphatase 2; catalytic subunit; beta isoform antibody; Protein phosphatase 2A catalytic subunit beta isoform antibody; Protein phosphatase type 2A catalytic subunit antibody; Serine/threonine protein phosphatase 2A catalytic subunit beta antibody; Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human PPP2CB
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    IHC 1:100-1:300
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
  • 基因功能参考文献：
    1. The GAS41-PP2Cbeta complex dephosphorylates p53 at serine 366 and regulates its stability PMID: 21317290
    2. Claspin may be one of the phosphoproteins through which PP2A(Aalpha/Cbeta) affects Chk1 phosphorylation when ATR is activated by human immunodeficiency virus-1 Vpr. PMID: 17210576
    3. These data strongly support a recent proposal that a segment at 8p21.3 contains crucial prostate cancer tumor suppressors. PMID: 18460741
  • 亚细胞定位：
    Cytoplasm. Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole. Note=In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.
  • 蛋白家族：
    PPP phosphatase family, PP-1 subfamily
  • 数据库链接：

    HGNC: 9300

    OMIM: 176916

    KEGG: hsa:5516

    STRING: 9606.ENSP00000221138

    UniGene: Hs.491440