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X Antibody

  • 货号：
    CSB-PA323774LA01WAW
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Woodchuck hepatitis B virus X Polyclonal antibody
  • Uniprot No.：
    P17401
  • 基因名：
    X
  • 别名：
    X antibody; Protein X antibody; HBx antibody; Peptide X antibody; pX antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Woodchuck hepatitis B virus
  • 免疫原：
    Recombinant Woodchuck hepatitis B virus Protein X protein (1-141AA)
  • 免疫原种属：
    Woodchuck hepatitis B virus
  • 标记方式：
    Non-conjugated

    本页面中的产品，X Antibody (CSB-PA323774LA01WAW)，的标记方式是Non-conjugated。对于X Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA323774LB01WAW X Antibody, HRP conjugated ELISA
    FITC CSB-PA323774LC01WAW X Antibody, FITC conjugated
    Biotin CSB-PA323774LD01WAW X Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma). Most of cytosolic activities involve modulation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential. May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC). Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation. This host complex would otherwise bind to viral episomal DNA, and prevents its transcription. Moderately stimulates transcription of many different viral and cellular transcription elements. Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
  • 亚细胞定位：
    Host cytoplasm. Host nucleus. Host mitochondrion.
  • 蛋白家族：
    Orthohepadnavirus protein X family