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  4. Recombinant Human Histone H1x (H1FX)

Recombinant Human Histone H1x (H1FX)

  • 货号：
    CSB-YP835674HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP835674HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP835674HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP835674HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP835674HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    H1FX
  • Uniprot No.：
  • 别名：
    H1 histone family member X; H1FX; H1X; H1X_HUMAN; Histone H1x; MGC15959; MGC8350
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-213
  • 氨基酸序列
    SVELEEALP VTTAEGMAKK VTKAGGSAAL SPSKKRKNSK KKNQPGKYSQ LVVETIRRLG ERNGSSLAKI YTEAKKVPWF DQQNGRTYLK YSIKALVQND TLLQVKGTGA NGSFKLNRKK LEGGGERRGA PAAATAPAPT AHKAKKAAPG AAGSRRADKK PARGQKPEQR SHKKGAGAKK DKGGKAKKTA AAGGKKVKKA AKPSVPKVPK GRK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
  • 基因功能参考文献：
    1. comparison of primary aa sequence with other human H1 subtypes, and H1x from different species, generation of specific antibody, expression in different cell lines PMID: 16006241
    2. These results suggest that the differential localization of H1x provides a mechanism for a control of H1x activity by means of shuttling between nuclear subcompartments instead of a controlled turnover of the protein. PMID: 17868027
    3. study concludes that the high expression of histone H1x in neuroendocrine tumours is probably due to the abundance of this protein in the cells from which these tumours originate PMID: 19108733
  • 亚细胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    Histone H1/H5 family
  • 组织特异性：
    Expressed ubiquitously.
  • 数据库链接：

    HGNC: 4722

    OMIM: 602785

    KEGG: hsa:8971

    STRING: 9606.ENSP00000329662

    UniGene: Hs.75307