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  4. Recombinant Mouse Zinc transporter ZIP6 (Slc39a6)

Recombinant Mouse Zinc transporter ZIP6 (Slc39a6)

  • 货号：
    CSB-CF804901MO
  • 规格：
  • 来源：
    in vitro E.coli expression system
  • 其他：

产品详情

  • 基因名：
  • Uniprot No.：
  • 别名：
    Slc39a6; Zip6; Zinc transporter ZIP6; Endoplasmic reticulum membrane-linked protein; Ermelin; Solute carrier family 39 member 6; Zrt- and Irt-like protein 6; ZIP-6
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    21-765
  • 氨基酸序列
    LHELQSTAAFSQTTEKINSNWEPGVNVDLAVTMQRHHLQQLFYRYGENDSLSVEGFRKLL QNIGIDKIKRVHIHHDHEHHADHEHHSDHEHHSDHEHHSDHEHHSDHEHHSDHEHHSHRS HTVAGKNNRKAFCPDLDSDNSGKNPRTSLGKGSRPAEHMNGRRNIKESASSSEVTSAVYN AVSEGTRFVETIETPKPGRRTKDVNPSTPPSITEKSRVGRLSRLARKKSNESVSEPRKSF MYSRNTNDNIQECFNTTKLLTSHGMSIQALLNATEFNYLCPAIINQIDARACLIHTASEK KAEIPPKTYSLQIAWLGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLS GDALLHLLPHSHASHQHSHSHEEPAMEMKRGPLFSHLSAQNIEESSYFDSTWKGLTALGG LYFMFLVEHVLTLIKQFKDKKKKNQKKPENDEDVESKKQLSKYDSQLSSNEEKVDPGERP ESYLRADSQEPSPFDSQQPTMLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQ SDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAGIATLAWMVIMGDGLHNFSD GLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYL GMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNA GILLGFGIMLLISIFEHKIVFRINF
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 10xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May act as a zinc-influx transporter.
  • 基因功能参考文献：
    1. PrP and ZIP6 inherited the ability to interact with NCAM1 from their common ZIP ancestors but have since diverged to control distinct posttranslational modifications of NCAM1. PMID: 28098160
    2. Zip 6 dysregulation was involved in enhanced inflammation during aging. PMID: 22981370
    3. mice fed low-Zn diet had reduced number of terminal deoxynucleotidyl transferase dUTP nick end labeling-positive cells compromised seminiferous tubule structure, and reduced Zip10 and Zip6 abundance (>50%; P < 0.5) compared with control diet PMID: 21248196
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ZIP transporter (TC 2.A.5) family
  • 组织特异性：
    Highly expressed in the brain and testis. In the brain strongly expressed in the CA1 and CA3 regions, Purkinje cells in cerebellum and dentate gyrus in hippocampus. In testis found in spermatids or mature sperms in the central areas of seminiferous tubule
  • 数据库链接：

    KEGG: mmu:106957

    STRING: 10090.ENSMUSP00000064667

    UniGene: Mm.21688