ACVR2A
ACVR2A，即激活素A型II型受体A，它是一种在TGF-β信号通路中起关键作用的膜受体。ACVR2A由ACVR2A基因编码，主要参与调节细胞的增殖、迁移和凋亡。其作用机制包括与激活素A结合后，招募并磷酸化I型激活素受体，通过SMAD2/3蛋白发出信号，进而影响细胞命运。在信号传导方面，ACVR2A的激活可以触发多种细胞内信号事件，包括细胞周期的调控和细胞行为的改变。在生物学意义上，ACVR2A对组织再生、细胞分化和肿瘤发展等过程具有重要影响。研究表明，ACVR2A在某些类型的癌症中表达下调，可能与肿瘤的转移潜能和患者的预后相关。
热销产品
ACVR2A Antibody (CSB-PA001260ESR2HU)
验证数据
Western blot
All lanes: Activin receptor type-2A antibody at 3μg/ml + Mouse brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 58, 46 kDa
Observed band size: 58 kDa
Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA001260ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA001260ESR2HU at dilution of 1:100
ACVR2A Antibodies
ACVR2A for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA001260ESR1HU | ACVR2A Antibody | Human | ELISA, IHC |
| CSB-PA001260ESR2HU | ACVR2A Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA070256 | ACVR2A Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA110386 | ACVR2A Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA104519 | ACVR2A Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA055681 | ACVR2A Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
ACVR2A Proteins
ACVR2A Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP001260MO1 CSB-EP001260MO1 CSB-BP001260MO1 CSB-MP001260MO1 CSB-EP001260MO1-B |
Recombinant Mouse Activin receptor type-2A (Acvr2a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001260MO | Recombinant Mouse Activin receptor type-2A (Acvr2a) | in vitro E.coli expression system |
ACVR2A Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP001260HU1 CSB-EP001260HU1 CSB-BP001260HU1 CSB-MP001260HU1 CSB-EP001260HU1-B |
Recombinant Human Activin receptor type-2A (ACVR2A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001260HU | Recombinant Human Activin receptor type-2A (ACVR2A) | in vitro E.coli expression system |
ACVR2A Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP001260RA1 CSB-EP001260RA1 CSB-BP001260RA1 CSB-MP001260RA1 CSB-EP001260RA1-B |
Recombinant Rat Activin receptor type-2A (Acvr2a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001260RA | Recombinant Rat Activin receptor type-2A (Acvr2a) | in vitro E.coli expression system |
ACVR2A Proteins for Xenopus laevis (African clawed frog)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP001260XBE1 CSB-EP001260XBE1 CSB-BP001260XBE1 CSB-MP001260XBE1 CSB-EP001260XBE1-B |
Recombinant Xenopus laevis Activin receptor type-2A (acvr2a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001260XBE | Recombinant Xenopus laevis Activin receptor type-2A (acvr2a) | in vitro E.coli expression system |
ACVR2A Proteins for Ovis aries (Sheep)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP631719SH CSB-EP631719SH CSB-BP631719SH CSB-MP631719SH CSB-EP631719SH-B |
Recombinant Sheep Activin receptor type-2A (ACVR2A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACVR2A Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP635678BO CSB-EP635678BO CSB-BP635678BO CSB-MP635678BO CSB-EP635678BO-B |
Recombinant Bovine Activin receptor type-2A (ACVR2A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACVR2A Proteins for Gallus gallus (Chicken)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP845865CH CSB-EP845865CH CSB-BP845865CH CSB-MP845865CH CSB-EP845865CH-B |
Recombinant Chicken Activin receptor type-2A (ACVR2A), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
