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CD74

CD74由长N-末端胞浆侧链与短C-末端胞外侧链构成,含NT、CLIP和CY结构域,胞内具酪氨酸/苏氨酸信号。它运输MHC II类分子,对免疫识别病原体至关重要。CD74见于B细胞及某些T细胞,参与淋巴发育。它激活ERK、PI3K和NF-κB等信号通路,具多种同种型,展现复杂调控功能。D74存在多种同种型,可能在不同细胞类型和生理病理条件下发挥特异性作用。

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Recombinant Human HLA class II histocompatibility antigen gamma chain (CD74), partial (Active)

验证数据

SDS
CSB-MP004956HU1(F2) SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
CSB-MP004956HU1(F2) ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD74 at 2 μg/ml can bind Anti-CD74 recombinant antibody (CSB-RA004956A1HU), the EC50 is 1.317-1.646 ng/mL.

Recombinant Mouse H-2 class II histocompatibility antigen gamma chain (Cd74), partial

验证数据

SDS
CSB-BP001262HU1 SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LCMS
CSB-BP001262HU1 LCMS-1

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP004956MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Cd74.

LCMS
CSB-BP001262HU1 LCMS-2

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP004956MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Cd74.


CD74 Antibodies

CD74 for Mus musculus (Mouse)

CD74 for Rattus norvegicus (Rat)

CD74 for Homo sapiens (Human)

CD74 Proteins

CD74 Proteins for Rattus norvegicus (Rat)

CD74 Proteins for Homo sapiens (Human)

CD74 Proteins for Mus musculus (Mouse)

CD74 ELISA Kit

CD74 ELISA Kit for Homo sapiens (Human)