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EPHA2

Ephrin type-A receptor 2 is a protein in humans that is encoded by EPHA2 gene. Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway.

EPHA2 Antibodies

EPHA2 for Homo sapiens (Human)

EPHA2 Proteins

EPHA2 Proteins for Homo sapiens (Human)

EPHA2 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

EPHA2 ELISA Kit

EPHA2 ELISA Kit for Homo sapiens (Human)