PTPN2
Tyrosine-protein phosphatase non-receptor type 2 is a protein in humans that is encoded by PTPN2 gene. Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also dephosphorylates non-receptor protein tyrosine kinases like JAK1, JAK2, JAK3, Src family kinases, STAT1, STAT3 and STAT6 either in the nucleus or the cytoplasm. Negatively regulates numerous signaling pathways and biological processes like hematopoiesis, inflammatory response, cell proliferation and differentiation, and glucose homeostasis. Plays a multifaceted and important role in the development of the immune system.
PTPN2 Antibodies
PTPN2 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA019031GA01HU | PTPN2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
PTPN2 Proteins
PTPN2 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP019031HU CSB-EP019031HU CSB-BP019031HU CSB-MP019031HU CSB-EP019031HU-B |
Recombinant Human Tyrosine-protein phosphatase non-receptor type 2 (PTPN2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PTPN2 Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP019031RA CSB-EP019031RA CSB-BP019031RA CSB-MP019031RA CSB-EP019031RA-B |
Recombinant Rat Tyrosine-protein phosphatase non-receptor type 2 (Ptpn2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |