SOS1

Son of sevenless homolog 1 is a protein in humans that is encoded by SOS1 gene. Son of sevenless homolog 1 is a protein in humans that is encoded by SOS1 gene. The protein promotes the exchange of Ras-bound GDP by GTP. Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity.