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中文名称:人内皮抑素(ES)酶联免疫试剂盒
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货号:CSB-E07973h
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规格:96T/48T
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价格:¥3600/¥2500
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其他:
产品详情
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产品描述:
The product CSB-E07973h is a sandwich ELISA kit developed to measure levels of human endostatin (ES) in serum, plasma, or tissue homogenates. The enzyme-substrate chromogenic reaction is also used to amplify the signal and quantify the levels of the analyte through the intensity of the colored product. The color intensity positively correlates with the amount of endostatin bound in the initial step.
Endostatin, a 20-kDa C-terminal cleavage product of type XVIII collagen, is an endogenous inhibitor known for its ability to inhibit the proliferation and migration of endothelial cells, angiogenesis, and tumor growth. Studies have proved that circulating endostatin increases significantly in patients with kidney and heart failure and may also contribute to disease progression. Endostatin inhibits angiogenesis by directly binding to both VEGFR1 and VEGFR2 and blocking VEGF interaction with Flt-1 and Flk-1 to prevent VEGF-induced tyrosine phosphorylation of VEGFR1 and VEGFR2 and all downstream signaling events.
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别名:FLJ27325, FLJ34914, KNO, KNO1, MGC74745, alpha 1 type XVIII collagen|antiangiogenic agent|endostatin|multi-functional protein MFP
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缩写:ES
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种属:Homo sapiens (Human)
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样本类型:serum, plasma, tissue homogenates
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检测范围:15.6 pg/ml -1000 pg/ml
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灵敏度:3.9 pg/ml
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Cardiovascular
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测定原理:quantitative
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测定方法:Sandwich
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精密度:
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线性度:
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回收率:
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数据处理:
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货期:3-5 working days
引用文献
- Correlation of Plasma Vascular Endothelial Growth Factor and Endostatin Levels with Symptomatic Intra-and Extracranial Atherosclerotic Stenosis in a Chinese Han Yu F.et al,J Stroke Cerebrovasc Dis. ,2017
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