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  4. Human Tetranectin(CLEC3B) ELISA kit

Human Tetranectin(CLEC3B) ELISA kit

  • 中文名称：
    人四连接素(CLEC3B)酶联免疫试剂盒
  • 货号：
    CSB-EL005531HU
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：

产品详情

  • 产品描述：
        CLEC3B，全名C型凝集素域家族3成员B，是一种跨膜蛋白，参与细胞黏附和信号传导等生物过程。它在肝病、癌症和心血管疾病等疾病中可能扮演重要角色。近年来，CLEC3B还被发现对肝细胞的保护作用，具有很高的研究价值。
        j9九游会登录入口首页生物所提供的Human Tetranectin(CLEC3B) ELISA kit属于ELISA检测试剂盒，采用双抗夹心法定量检测人血清、血浆、组织匀浆样本中的CLEC3B，其灵敏度为0.39 ng/ml，检测范围为1.56 ng/ml- 100 ng/ml。
     
  • 别名：
    C type lectin domain family 3 member B ELISA Kit; C-type lectin domain family 3 member B ELISA Kit; Clec3b ELISA Kit; Plasminogen kringle 4 binding protein ELISA Kit; Plasminogen kringle 4-binding protein ELISA Kit; TETN_HUMAN ELISA Kit; Tetranectin (plasminogen binding protein) ELISA Kit; Tetranectin ELISA Kit; TN ELISA Kit; TNA ELISA Kit
  • 缩写：
    CLEC3B
  • Uniprot No.：
  • 种属：
    Homo sapiens (Human)
  • 样本类型：
    serum, plasma, tissue homogenates
  • 检测范围：
    1.56 ng/ml- 100 ng/ml
  • 灵敏度：
    0.39 ng/ml
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Others
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 数据处理：
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 最新研究进展：
    CLEC3B是一种由CLEC3B基因编码的蛋白质，也被称为牙龈沟液蛋白GCP-2。CLEC3B在人体免疫系统中发挥着重要作用，可通过识别病原体或潜在损伤信号，介导免疫反应。最近的研究表明，CLEC3B还可能与其他生物学过程有关，如肝脏再生、炎症反应和肿瘤的生长和转移等。此外，CLEC3B的检测也被用于诊断某些疾病和监测其疾病进程。
     
  • 功能：
    Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.
  • 基因功能参考文献：
    1. Low CLEC3B expression is associated with clear cell renal cell carcinoma. PMID: 30066941
    2. The present study identified the CLEC3B p.S106G as a novel longevity-associated variant, raising the novel hypothesis that tetranectin, encoded by CLEC3B, plays a role in human longevity and aging PMID: 27154906
    3. TMEM88, CCL14, and CLEC3B genes were stable and available in predicting the survival and palindromia time of hepatocellular carcinoma. These genes could function as potential prognostic genes contributing to improve patients' outcomes and survival PMID: 28718365
    4. study suggests that increased serum TN level is associated with the presence and severity of diseased coronary arteries in patients with stable CAD. PMID: 26621497
    5. results predict that a positive TN expression of both tumour tissue and serum points to a more favourable outcome for ovarian cancer patients PMID: 25846370
    6. analyze the immunohistochemical localization of tetranectin in gastric adenocarcinomas and the adjacent tissues of the wall of the stomach PMID: 11962752
    7. Tetranectin may play an important role in the survival of islets in the liver after islet transplantation. PMID: 15848710

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  • 亚细胞定位：
    Secreted.
  • 组织特异性：
    Found in plasma.
  • 数据库链接：

    HGNC: 11891

    OMIM: 187520

    KEGG: hsa:7123

    STRING: 9606.ENSP00000296130

    UniGene: Hs.476092