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  4. Monkey Complement 3(C3)ELISA Kit

Monkey Complement 3(C3)ELISA Kit

  • 中文名称：
    猴子补体蛋白3(C3)酶联免疫试剂盒
  • 货号：
    CSB-E16528Mk
  • 规格：
    96T/48T
  • 价格：
    ￥4200/￥3000
  • 其他：

产品详情

  • 产品描述：

    This Monkey Complement 3 (C3) ELISA Kit was designed for the quantitative measurement of Monkey Complement 3 (C3) protein in serum, plasma, cell culture supernates. It is a Sandwich ELISA kit, its detection range is 4.68 ng/mL-300 ng/mL and the sensitivity is 1.17 ng/mL.

  • 别名：
    C3Complement C3 [Cleaved into: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; C3-beta-c ELISA kit; C3bc); Acylation stimulating protein ELISA kit; ASP ELISA kit; C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2] ELISA kit
  • 缩写：
  • Uniprot No.：
  • 种属：
    Monkey
  • 样本类型：
    serum, plasma, cell culture supernates
  • 检测范围：
    4.68 ng/mL-300 ng/mL
  • 灵敏度：
    1.17 ng/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Cancer
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%      
    Three samples of known concentration were tested twenty times on one plate to assess.  
    Inter-assay Precision (Precision between assays): CV%<10%      
    Three samples of known concentration were tested in twenty assays to assess.    
                 
  • 标准曲线：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/ml OD1 OD2 Average Corrected  
    300 2.276 2.296 2.286 2.144  
    150 1.896 1.854 1.875 1.733  
    75 1.520 1.539 1.530 1.388  
    37.5 1.195 1.174 1.185 1.043  
    18.75 0.864 0.883 0.874 0.732  
    9.37 0.531 0.557 0.544 0.402  
    4.68 0.345 0.365 0.355 0.213  
    0 0.141 0.143 0.142 　  
  • 数据处理：
  • 货期：
    3-5 working days

产品评价

问答及客户评论

■ 客户评论
  • Tested application: ELISA
    Test sample: Serum
    Species: Monkey
    Review: The difference between the kit batches is small, and the test repeatability is better!
  • Tested application: ELISA
    Test sample: Serum
    Species: Monkey
    Review: The difference between the kit batches is small, and the test repeatability is better!
  • Tested application: ELISA
    Test sample: Serum
    Species: Monkey
    Review: The difference between the kit batches is small, and the test repeatability is better!

靶点详情

  • 功能：
    C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.; Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. In chronic inflammation, acts as a chemoattractant for neutrophils.; Acts as a chemoattractant for neutrophils in chronic inflammation.; adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-internalization and recycling of C5AR2.
  • 基因功能参考文献：
    1. The structure of bovine C3 clearly demonstrates that the main chain around the thioester undergoes a helical transition upon activation, a rearrangement that is proposed to be the basis for the high level of reactivity of the thioester group. PMID: 16831446
  • 亚细胞定位：
    Secreted.
  • 数据库链接：