Mouse Cluster of differentiation 30,CD30 ELISA Kit
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中文名称:小鼠CD30分子(CD30)酶联免疫试剂盒
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货号:CSB-E04525m
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规格:96T/48T
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价格:¥3800/¥2500
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其他:
产品详情
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别名:Tnfrsf8 ELISA Kit; Tumor necrosis factor receptor superfamily member 8 ELISA Kit; CD30L receptor ELISA Kit; Lymphocyte activation antigen CD30 ELISA Kit; CD antigen CD30 ELISA Kit
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缩写:
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Uniprot No.:
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种属:Mus musculus (Mouse)
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检测范围:15.6 pg/mL-1000 pg/mL
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灵敏度:3.9 pg/mL
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Others
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货期:3-5 working days
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靶点详情
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功能:Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
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基因功能参考文献:
- This study demonstrated the amelioration of MOG35-55 peptide-induced active EAE in CD30 KO mice. CD30 was expressed limitedly on CD4 T cells at the induction phase of experimental autoimmune encephalomyelitis. PMID: 26857493
- Data indicate that CD30L/CD30 axis plays a modulatory role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE). PMID: 25533628
- role in the maintenance and activation of IL-17A-producing gammadelta T cells PMID: 23549449
- These results suggest that CD30 signaling plays an important role in the activation of IL-17A-producing Vgamma1(-) Vgamma4(-) gammadelta T cells bearing Vgamma6 at an early stage of BCG infection. PMID: 23918785
- Interference of the CD30-CD30L pathway reduces atherosclerosis development. PMID: 23087358
- CD30L/CD30 pathway acts as an accelerator of enteritis in a murine disease model PMID: 22451116
- role of CD30L/CD30 interactions in allergic rhinitis; results suggest that CD30L plays an important role in allergic rhinitis PMID: 21739429
- Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice. PMID: 21788408
- Studies demonstrate that CD30L/CD30 signaling executed by the T-T cell interaction plays a critical role in Th17 cell differentiation. PMID: 20639486
- CD30 can signal in a completely TCR-independent fashion to induce IL-13 production by effector T cells. PMID: 12193714
- Immunity to CD30 could play a role in Marek disease lymphoma regression. PMID: 15356338
- Deficiencies in OX40 and CD30 signals were additive, secondary Ab responses were ablated.OX40/CD30 double-knockout OTII transgenic T cells fail to survive compared with normal T cells when cocultured with CD4(+)CD3(-) cells in vitro. PMID: 15778343
- CD30 plays an important role in the generation of long-lived memory CD8+ T cells, at least partly by triggering homing receptors for T(central memory) cells. PMID: 16177108
- early CD30 signaling is critical for regulatory T cells-mediated acute graft-versus-host disease protection after major MHC-mismatch bone marrow transplantation PMID: 17068147
- These results indicate that CD30 is a regulator of T(h)2 responses in the effector-memory phase and a regulator of IL-13 production in memory cells in the lung. PMID: 18089617
- CD30L/CD30 signaling is involved in development of both OXA- and TNBS-induced colitis. Modulation of CD30L/CD30 signaling by mAb could be a novel biologic therapy for inflammatory bowel diseases. PMID: 18242212
- CD30 and OX40 signals are both required for the survival but not commitment of CD4 T helper type 1 (Th1) cells. PMID: 18292503
- Signaling executed by CD30positive T cell interaction with CD30Lpositive T cells plays a critical role in amplification of T helper type (Th)1 responses that able to produce interferon-gamma against Mycobacterium bovis bacillus Calmette-Guerin infection. PMID: 18941223
- ko mice exhibite delayed structuring of pulmonary granulomas and reduced recruitment of lymphocytes after infection with erogenic Mycobacterium avium PMID: 19250702
- CD30 signals from lymphoid tissue inducer cells were a primitive mechanism to recruit and prime CD4 T cells PMID: 19342654
- Data demonstrate that the crucial role of CD30 signaling in the development of acute asthma may be taken over by other costimulatory molecules like OX40 after long-term exposure to the antigen. PMID: 19544310
- Following infection with murine cytomegalovirus, CD30 is necessary for preserving the lymphoid microenvironment by enhancing the protective function of NK cells. PMID: 19731363
- signals through CD30 and OX40 are required for the survival of CD4(+) T cells within the small intestine lamina propria. PMID: 19786532
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亚细胞定位:Cell membrane; Single-pass type I membrane protein.
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组织特异性:Detected in thymus and in activated splenocytes.
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数据库链接:
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