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  4. Mouse Pancreatic Lipase(PL)ELISA Kit

Mouse Pancreatic Lipase(PL)ELISA Kit

  • 中文名称：
    小鼠胰脂肪酶(PL)酶联免疫试剂盒
  • 货号：
    CSB-E16930m
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：

产品详情

  • 产品描述：

    CUSABIO's mouse pancreatic lipase (PL) ELISA kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse PL in serum, plasma, or tissue homogenates. This assay uses the sandwich enzyme immunoassay technique in combination with the enzyme-substrate chromogenic reaction to quantify the analyte in the sample. The color develops positively to the amount of PL in samples. The color intensity is measured at 450 nm via a microplate reader.

    PL is usually secreted by the pancreatic acinar cells and transferred to the duodenum to participate in the hydrolysis and digestion of fat, cholesterol esters, and fat-soluble vitamins. It is critical for the digestion and absorption of dietary fats and plays an important role in the regulation of gastric emptying and pancreatic and biliary secretion after ingestion of fat in humans. Plasma levels of pancreatic lipase are routinely measured in the diagnosis of pancreatic dysfunction. Congenital pancreatic lipase deficiency is a rare autosomal recessive exocrine pancreatic failure featured with reduced absorption of dietary fat and greasy voluminous stools, but apparent normal development and an overall good state of health.

  • 别名：
    PnlipPancreatic triacylglycerol lipase ELISA Kit; PL ELISA Kit; PTL ELISA Kit; Pancreatic lipase ELISA Kit; EC 3.1.1.3 ELISA Kit
  • 缩写：
    PL
  • Uniprot No.：
  • 种属：
    Mus musculus (Mouse)
  • 样本类型：
    serum, plasma, tissue homogenates
  • 检测范围：
    62.5 mU/mL-4000 mU/mL
  • 灵敏度：
    15.6 mU/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Metabolism
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 数据处理：
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 功能：
    Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones.
  • 基因功能参考文献：
    1. the ability to degrade unfolded protein decreases in the aging pancreas, and this leads to reduction of pancreatic lipase activity and a decrease in lipid absorption PMID: 25033985
    2. pancreatic triglyceride lipase has a critical role in dietary cholesterol absorption and a minimal role in dietary fat absorption in mice PMID: 12915407
    3. PTL and CEL serve complementary functions, working together to mediate the absorption of a major portion of dietary fat and fat-soluble vitamin esters PMID: 17604277
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    AB hydrolase superfamily, Lipase family
  • 组织特异性：
    Pancreas.
  • 数据库链接：