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  4. Mouse chemokine (C-X-C motif) ligand 17 (CXCL17) ELISA kit

Mouse chemokine (C-X-C motif) ligand 17 (CXCL17) ELISA kit

  • 中文名称：
    小鼠趋化因子配体17(CXCL17)酶联免疫试剂盒
  • 货号：
    CSB-EL006246MO
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：

产品详情

  • 产品描述：

    This Mouse CXCL17 ELISA Kit was designed for the quantitative measurement of Mouse CXCL17 protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 37.5 pg/mL-2400 pg/mL and the sensitivity is 9.375 pg/mL.

  • 别名：
    Cxcl17 ELISA kit; Vcc1C-X-C motif chemokine 17 ELISA kit; 6-Cys CXCL17 ELISA kit; 13.6 kDa protein ELISA kit; VEGF coregulated chemokine 1) [Cleaved into: 4-Cys CXCL17] ELISA kit
  • 缩写：
    CXCL17
  • Uniprot No.：
  • 种属：
    Mus musculus (Mouse)
  • 样本类型：
    serum, plasma, tissue homogenates
  • 检测范围：
    37.5 pg/mL-2400 pg/mL
  • 灵敏度：
    9.375 pg/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Immunology
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 数据处理：
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 功能：
    Chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions.
  • 基因功能参考文献：
    1. CXCL17 attenuates Imiquimod -induced psoriasis-like skin inflammation by recruiting myeloid-derived suppressor cells and regulatory T cells , which may be important for regulating excessive inflammation in psoriasis skin. PMID: 28389593
    2. CXCL17 is a novel macrophage chemoattractant that operates in mucosal tissues as a major regulator of inflammatory responses. PMID: 24973458
    3. These results suggest that aberrant expression of CXCL17 in tumor cells recruits immature myeloid-derived cells and promotes tumor progression through angiogenesis. PMID: 22952881
    4. VCC-1 plays a role in angiogenesis and possibly in the development of tumors in some tissue types[VCC-1] PMID: 16989774
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Intercrine alpha (chemokine CxC) family
  • 组织特异性：
    Detected in lung, trachea, lung, tongue thyroid, submaxillary gland, epididymis, and uterus tissues and at a lower level in ovary, prostate and in intestinal tissues.
  • 数据库链接：

    KEGG: mmu:232983

    UniGene: Mm.10545