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中文名称:大鼠基质金属蛋白酶1(MMP-1/Collagenase I)酶联免疫试剂盒
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货号:CSB-E07416r
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规格:96T/48T
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价格:¥3600/¥2500
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其他:
产品详情
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产品描述:MMP1(Matrix Metalloproteinase-1),又称Kollagenase-1,是一种结构相关的锌依赖性内切酶,参与许多生理和病理过程中的基质降解。MMP1能够分解胶原、弹性蛋白、纤维连接蛋白等成分,具有重要的组织修复和调节作用。在结缔组织的代谢中,MMP1的含量是关键的生物学指标,过高或过低都会对细胞的正常功能产生影响。j9九游会登录入口首页生物所提供的Rat matrix metalloproteinase 1(MMP-1/Collagenase I) ELISA kit属于ELISA检测试剂盒,采用双抗夹心法定量检测大鼠血清、血浆、组织匀浆样本中的MMP1,其灵敏度为0.058 ng/ml,检测范围为0.235 ng/ml - 15 ng/ml。
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别名:Mmp1Interstitial collagenase ELISA Kit; EC 3.4.24.7 ELISA Kit; Fibroblast collagenase ELISA Kit; Matrix metalloproteinase-1 ELISA Kit; MMP-1 ELISA Kit; Myocardial collagenase ELISA Kit; Fragment ELISA Kit
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缩写:
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Uniprot No.:
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种属:Rattus norvegicus (Rat)
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样本类型:serum, plasma, tissue homogenates
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检测范围:0.235 ng/ml - 15 ng/ml
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灵敏度:0.058 ng/ml
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Cancer
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测定原理:quantitative
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测定方法:Sandwich
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精密度:
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线性度:
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回收率:
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数据处理:
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货期:3-5 working days
引用文献
- Photoaging induced by long-term exposure to UV irradiation and amelioration by Skipjack tuna skin hydrolysates: Targeting inhibition of MAPK and NF-κB signaling hyperactivation D Xu,Journal of Functional Foods,2022
- Dietary Supplementation with Palmitoyl-Glucosamine Co-Micronized with Curcumin Relieves Osteoarthritis Pain and Benefits Joint Mobility E Gugliandolo,Animals,2020
- Ethanolic and Aqueous Extracts of Avocado (Persea americana) Seeds Attenuates Doxorubicin-Induced Cardiotoxicity in Male Albino Rats G Shamlan,Arabian Journal for Science and Engineering,2020
- Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain Cordaro M, et al,Arthritis Research & Therapy,2019
- A novel composite formulation of palmitoylethanolamide and quercetin decreases inflammation and relieves pain in inflammatory and osteoarthritic pain models Britti D.et al,BMC Vet Res.,2017
- Adelmidrol, in combination with hyaluronic acid, displays increased anti-inflammatory and analgesic effects against monosodium iodoacetate-induced osteoarthritis in rats Rosanna Di Paola.et al,Arthritis Research & Therapy,2016
- Matrix metalloproteinases are possible targets inmonocrotaline-induced pulmonary hypertension: investigationof anti-remodeling effects of alagebrium and everolimus Atl.et al,Anatolian journal of cardiology,2016
相关产品
靶点详情
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最新研究进展:MMP1,全名为基质金属蛋白酶-1,是一种广泛存在于人体组织中的酶类分子。MMP1主要参与胶原蛋白的降解和清除过程,在组织再生、炎症、肿瘤转移等多种生理和病理过程中发挥重要作用。最近的研究表明,MMP1在多种癌症的发生和发展中发挥关键作用,成为了一个重要的治疗靶点。此外,MMP1还与关节炎、动脉粥样硬化等疾病的发生和发展密切相关,成为了重要的生物标志物和疾病预测因子。针对这些酶的抑制剂已成为研究的热点,可以用于疾病的预防和治疗。
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功能:Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. May play a role in the deterioration of the heart wall extracellular matrix proteins during the onset of dilated cardiomyopathy.
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亚细胞定位:Secreted, extracellular space, extracellular matrix.
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蛋白家族:Peptidase M10A family
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数据库链接:
UniGene: Rn.79007
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