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  4. Sheep Follicle Stimulating Hormone (FSH) ELISA kit

Sheep Follicle Stimulating Hormone (FSH) ELISA kit

  • 中文名称：
    绵羊卵泡刺激素(FSH)酶联免疫试剂盒
  • 货号：
    CSB-E13170Sh
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：

产品详情

  • 别名：
    FSHBFollitropin subunit beta ELISA kit; Follicle-stimulating hormone beta subunit ELISA kit; FSH-B ELISA kit; FSH-beta ELISA kit; Follitropin beta chain ELISA kit
  • 缩写：
    FSH
  • Uniprot No.：
  • 种属：
    Ovis aries (Sheep)
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Signal Transduction
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 精密度：
     
  • 线性度：
     
  • 回收率：
     
  • 标准曲线：
     
  • 数据处理：
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 功能：
    Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
  • 基因功能参考文献：
    1. A novel GnRH response element between -750 bp and -232 bp of the ovine FSHB promoter. PMID: 23874399
    2. Data suggest that dietary components (phytoestrogens here) down-regulate basal secretion/total FSH (CGA+FSHB) production yet up-regulate gonadotropin-releasing hormone agonist-induced luteinizing hormone (CGA+LHB) secretion in gonadotrophs. PMID: 24050980
    3. In ewes, infusion with genistein decreased the level FSH-beta in the adenohypophysis. PMID: 15531133
    4. Activation of TAK1 (and probably p38-MAPK), but not Smad3, is necessary for triggering induction of oFSHbeta by activin. PMID: 16081641
    5. Activin gathers Smads and Smad-associated proteins at the promoter region to regulate expression of the ovine FSHB and overall follitropin production. PMID: 17584958

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Glycoprotein hormones subunit beta family
  • 数据库链接：

    KEGG: oas:443387

    UniGene: Oar.430