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AAMP Antibody

  • 中文名称：
    AAMP多克隆抗体
  • 货号：
    CSB-PA001021GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q13685
  • 基因名：
    AAMP
  • 别名：
    AAMPAngio-associated migratory cell protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human AAMP
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway.
  • 基因功能参考文献：
    1. AAMP Regulates Endothelial Cell Migration and Angiogenesis Through RhoA/Rho Kinase Signaling. PMID: 26350504
    2. High levels of AAMP levels were associated with breast cancer progression and metastasis PMID: 23564791
    3. angio-associated migratory cell protein was identified as a novel interacting partner of both TPalpha and TPbeta isoforms of the thromboxane A2 receptor PMID: 21172430
    4. important functional role of AAMP in the migration of smooth muscle cells (SMCs), identifying AAMP as a potential target to limit lesion formation after injury. PMID: 18634987
    5. Data support a new function of AAMP in regulating innate immune responses initiated by the NLR protein Nod2. PMID: 19535145

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  • 亚细胞定位：
    Cell membrane. Cytoplasm.
  • 组织特异性：
    Expressed in metastatic melanoma, liver, skin, kidney, heart, lung, lymph node, skeletal muscle and brain, and also in A2058 melanoma cells and activated T-cells (at protein level). Expressed in blood vessels. Strongly expressed in endothelial cells, cyto
  • 数据库链接：

    HGNC: 18

    OMIM: 603488

    KEGG: hsa:14

    STRING: 9606.ENSP00000248450

    UniGene: Hs.83347