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AASDHPPT Antibody

  • 货号：
    CSB-PA648080
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of COLO205 cells using AASD-PPT Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9NRN7
  • 基因名：
    AASDHPPT
  • 别名：
    4' phosphopantetheinyl transferase antibody; 4'-phosphopantetheinyl transferase antibody; AASD PPT antibody; AASD-PPT antibody; AASDHPPT antibody; ADPPT_HUMAN antibody; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase antibody; Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase antibody; CGI 80 antibody; HAH P antibody; L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase antibody; LYS2 antibody; LYS5 antibody; LYS5 ortholog antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human AASD-PPT.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A, regardless of whether the CoA is presented in the free thiol form or as an acetyl thioester, to a serine residue of a broad range of acceptors including the acyl carrier domain of FASN.
  • 基因功能参考文献：
    1. Our study identifies human PPT as the FDH-modifying enzyme and supports the hypothesis that mammals utilize a single enzyme for all phosphopantetheinylation reactions. PMID: 19933275
    2. humans appear to utilize a single, broad specificity enzyme, 4'-phosphopantetheine transferase, for all posttranslational 4'-phosphopantetheinylation reactions PMID: 12815048
  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    P-Pant transferase superfamily, AcpS family
  • 组织特异性：
    Detected in heart, skeletal muscle, placenta, testis, brain, pancreas, liver and kidney.
  • 数据库链接：

    HGNC: 14235

    OMIM: 607756

    KEGG: hsa:60496

    STRING: 9606.ENSP00000278618

    UniGene: Hs.524009