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AATK Antibody

  • 货号：
    CSB-PA179611
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA179611(AATK Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA179611(AATK Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q6ZMQ8
  • 基因名：
    AATK
  • 别名：
    AATK antibody; AATYK antibody; AATYK1 antibody; Apoptosis associated tyrosine kinase antibody; Apoptosis-associated tyrosine kinase antibody; Brain apoptosis associated tyrosine kinase antibody; Brain apoptosis-associated tyrosine kinase antibody; CDK5 binding protein antibody; CDK5-binding protein antibody; KIAA0641 antibody; Lemur tyrosine kinase 1 antibody; LMR1 antibody; LMTK1 antibody; LMTK1_HUMAN antibody; p35 binding protein antibody; p35-binding protein antibody; p35BP antibody; Serine/threonine protein kinase LMTK1 antibody; Serine/threonine-protein kinase LMTK1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human AATK
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in neuronal differentiation.
  • 基因功能参考文献：
    1. ATKK was validated as a target gene of miR-558, and upregulation of miR-558 was observed in radioresistant lung cancer cells. Additionally, ectopic overexpression of ATKK partially but significantly reduced the miR-558-induced radioresistance. PMID: 27485693
    2. Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein. PMID: 14521924
    3. This paper deals with the mouse ortholog. PMID: 17651901
  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Note=Predominantly perinuclear.
  • 蛋白家族：
    Protein kinase superfamily, Tyr protein kinase family
  • 组织特异性：
    Expressed in brain.
  • 数据库链接：

    HGNC: 21

    OMIM: 605276

    KEGG: hsa:9625

    STRING: 9606.ENSP00000324196

    UniGene: Hs.514575