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ABI3 Antibody

  • 货号：
    CSB-PA873732LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: ABI3 antibody at 5μg/ml + Mouse heart tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 40, 39 kDa
      Observed band size: 40 kDa
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA873732LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA873732LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ABI3 Polyclonal antibody
  • Uniprot No.：
    Q9P2A4
  • 基因名：
    ABI3
  • 别名：
    ABI3 antibody; NESHABI gene family member 3 antibody; New molecule including SH3 antibody; Nesh antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human ABI gene family member 3 protein (1-366AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ABI3 Antibody (CSB-PA873732LA01HU)，的标记方式是Non-conjugated。对于ABI3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA873732LB01HU ABI3 Antibody, HRP conjugated ELISA
    FITC CSB-PA873732LC01HU ABI3 Antibody, FITC conjugated
    Biotin CSB-PA873732LD01HU ABI3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May inhibit tumor metastasis. In vitro, reduces cell motility.
  • 基因功能参考文献：
    1. Low ABI3 expression is associated with thyroid carcinomas. PMID: 27036019
    2. Data show that protein-altering changes are in PLCG2, ABI3, and TREM2 genes highly expressed in microglia and highlight an immune-related protein-protein interaction network in Alzheimer's disease. PMID: 28714976
    3. Result links ABI3 to the pathogenesis and progression of some cancers and suggests that ABI3 or its pathway might have interest as therapeutic target. PMID: 21223585
    4. Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells. PMID: 11956071
  • 亚细胞定位：
    Cytoplasm. Note=Colocalizes with PAK2 at leading edge of cells.
  • 蛋白家族：
    ABI family
  • 组织特异性：
    Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle.
  • 数据库链接：

    HGNC: 29859

    OMIM: 606363

    KEGG: hsa:51225

    STRING: 9606.ENSP00000225941

    UniGene: Hs.130719