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ACAP2 Antibody

  • 货号：
    CSB-PA001132GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q15057
  • 基因名：
  • 别名：
    ACAP 2 antibody; ACAP2 antibody; ACAP2_HUMAN antibody; ANK repeat and PH domain-containing protein 2 antibody; Arf GAP with coiled coil ANK repeat and PH domain containing protein 2 antibody; Arf GAP with coiled coil ANK repeat and PH domains 2 antibody; Arf-GAP with coiled-coil antibody; ArfGAP with coiled coil ankyrin repeat and PH domains 2 antibody; CENT B 2 antibody; Centaurin beta2 antibody; Centaurin-beta-2 antibody; CENTB 2 antibody; CENTB2 antibody; Cnt b2 antibody; Cnt-b2 antibody; Cntb2 antibody; KIAA0041 antibody; Similar to yeast ZINC FINGER PROTEIN GCS1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human ACAP2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).
  • 基因功能参考文献：
    1. The down-regulation of circRNA-ACAP2 promoted miR-21-5p expression, which further suppressed the transcription and translation of Tiam1. PMID: 30212824
    2. ACAP2 is a functional homolog of C. elegans CNT-1 and its inactivation or downregulation in human cells may contribute to cancer development PMID: 25853217
    3. ACAP2 has robust, constitutive Arf6 GAP activity in vivo, with little activity toward Arf1. PMID: 18003747
    4. Centaurin beta2/KIAA0041, is a member of the centaurin family of ADP-ribosylation factor directed GTPase-activating proteins. Binding of phosphoinositides to a pleckstrin homology domain may regulate subcellular localisation and activity. PMID: 11050434
  • 亚细胞定位：
    Endosome membrane; Peripheral membrane protein.
  • 组织特异性：
    Widely expressed. Highest level in lung.
  • 数据库链接：

    HGNC: 16469

    OMIM: 607766

    KEGG: hsa:23527

    STRING: 9606.ENSP00000324287

    UniGene: Hs.593373