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ACAT2 Antibody

  • 货号：
    CSB-PA861152ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA861152ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ACAT2 Polyclonal antibody
  • Uniprot No.：
    Q9BWD1
  • 基因名：
    ACAT2
  • 别名：
    Acat2 antibody; acetoacetyl CoA thiolase antibody; acetoacetyl Coenzyme A thiolase antibody; Acetyl CoA acetyltransferase antibody; Acetyl CoA transferase like protein antibody; acetyl Coenzyme A acetyltransferase 2 antibody; Acetyl-CoA acetyltransferase antibody; Acetyl-CoA transferase-like protein antibody; Acyl Coenzyme A cholesterol acyltransferase 2 antibody; Cytosolic acetoacetyl-CoA thiolase antibody; cytosolic antibody; SOAT2 antibody; THIC_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Acetyl-CoA acetyltransferase, cytosolic protein (1-97AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the biosynthetic pathway of cholesterol.
  • 基因功能参考文献：
    1. results demonstrate that the low-level expression of human ACAT2 gene with specific CpG-hypomethylated promoter is regulated by the C/EBP transcription factors in monocytic cells, and imply that the lowly expressed ACAT2 catalyzes the synthesis of certain CE/SE that are assembled into lipoproteins for the secretion PMID: 27688151
    2. Results show that DLAT and ACAT2 as upstream acetyltransferases of K76 and K294 in 6PGD protein. PMID: 25042803
    3. Reduced ACAT2 is associated with impaired butyrate oxidation in ulcerative colitis. PMID: 21987487
    4. Data describe the high resolution structure of human cytosolic acetoacetyl-CoA thiolase (CT), both unliganded (at 2.3 angstroms resolution) and in complex with CoA (at 1.6 angstroms resolution). PMID: 15733928
    5. The increased NPC1L1 and ACAT2 mRNA levels in gallstone patients might indicate an upregulated absorption and esterification of cholesterol in the small intestine. PMID: 19071091

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  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    Thiolase family
  • 数据库链接：

    HGNC: 94

    OMIM: 100678

    KEGG: hsa:39

    STRING: 9606.ENSP00000356015

    UniGene: Hs.571037