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ACHE Antibody

  • 货号：
    CSB-PA001154EA01BO
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Bovine ACHE Polyclonal antibody
  • Uniprot No.：
    P23795
  • 基因名：
    ACHE
  • 别名：
    ACHEAcetylcholinesterase antibody; AChE antibody; EC 3.1.1.7 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Bovine
  • 免疫原：
    Recombinant Bovine Acetylcholinesterase protein (31-613AA)
  • 免疫原种属：
    Bovine
  • 标记方式：
    Non-conjugated

    本页面中的产品，ACHE Antibody (CSB-PA001154EA01BO)，的标记方式是Non-conjugated。对于ACHE Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA001154EB01BO ACHE Antibody, HRP conjugated ELISA
    FITC CSB-PA001154EC01BO ACHE Antibody, FITC conjugated
    Biotin CSB-PA001154ED01BO ACHE Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
  • 基因功能参考文献：
    1. To date, AChE and BChE are the only proteins known that include polyproline tetramer organizing peptides in their tetrameric structure. PMID: 23352838
    2. The monomeric form of AChE in fetal bovine serum is trimmed at the carboxyl-terminus compared to the tetrameric form, consistent with the involvement of C-terminal amino acids in the assembly of monomers into tetramers. PMID: 14690439
    3. findings show that AChE induces a remarkable aggregation of PrP 106-126 with a mechanism similar to that described for amyloid beta protein PMID: 16750169
    4. In this work, the catalytic activity of acetylcholinesterase (AChE) immobilized on these materials was investigated, using neostigmina as AChE inhibitor. PMID: 17208293
    5. Results strongly support the role of acetylcholinesterase in triggering amyloidogenesis and the potential therapeutic relevance of peripheral site blocker compounds. PMID: 19038345
    6. Hydrolysis of acetylthiocoline, o-nitroacetanilide and o-nitrotrifluoroacetanilide by fetal bovine serum acetylcholinesterase PMID: 19292875

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  • 亚细胞定位：
    Cell junction, synapse. Secreted. Cell membrane; Peripheral membrane protein.; [Isoform H]: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
  • 蛋白家族：
    Type-B carboxylesterase/lipase family
  • 数据库链接：

    KEGG: bta:540446

    STRING: 9913.ENSBTAP00000001517

    UniGene: Bt.1299