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  4. ACOT11 Antibody

ACOT11 Antibody

  • 货号：
    CSB-PA908870
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA908870(ACOT11 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA908870(ACOT11 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal kidney tissue, Human fetal lung tissue, Primary antibody: CSB-PA908870(ACOT11 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 90 seconds
  • 其他：

产品详情

  • Uniprot No.：
    Q8WXI4
  • 基因名：
    ACOT11
  • 别名：
    ACO11_HUMAN antibody; ACOT 11 antibody; ACOT11 antibody; Acyl CoA thioester hydrolase 11 antibody; Acyl CoA thioesterase 11 antibody; Acyl coenzyme A thioesterase 11 antibody; Acyl-CoA thioester hydrolase 11 antibody; Acyl-CoA thioesterase 11 antibody; Acyl-coenzyme A thioesterase 11 antibody; Adipose associated thioesterase antibody; Adipose-associated thioesterase antibody; BFIT 1 antibody; BFIT 2 antibody; BFIT antibody; BFIT1 antibody; BFIT2 antibody; Brown fat inducible thioesterase antibody; Brown fat-inducible thioesterase antibody; KIAA0707 antibody; OTTHUMP00000046722 antibody; StAR related lipid transfer (START) domain containing 14 antibody; STARD 14 antibody; STARD14 antibody; START domain containing 14 antibody; THEA antibody; THEM 1 antibody; THEM1 antibody; Thioesterase adipose associated antibody; Thioesterase superfamily member 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human ACOT11
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.
  • 基因功能参考文献：
    1. The N-terminal region of human fat inducible thioesterase variant 2 constitutes a mitochondrial location signal sequence, which undergoes mitochondrion-dependent posttranslational cleavage. PMID: 22897136
    2. BFIT supports the transition of thermogenic brown adipose tissue towards increased metabolic activity, probably through alteration of intracellular fatty acyl-CoA concentration. PMID: 11696000
  • 亚细胞定位：
    Mitochondrion matrix. Cytoplasm.
  • 组织特异性：
    Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue.
  • 数据库链接：

    HGNC: 18156

    OMIM: 606803

    KEGG: hsa:26027

    STRING: 9606.ENSP00000360366

    UniGene: Hs.745173