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ACSM3 Antibody

  • 货号：
    CSB-PA709601ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: Acyl-coenzyme A synthetase ACSM3, mitochondrial antibody at 10μg/ml
      Lane 1: 293T whole cell lysate
      Lane 2: Mouse kidney tissue
      Lane 3: A431 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 67, 50 kDa
      Observed band size: 67 kDa
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA709601ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA709601ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ACSM3 Polyclonal antibody
  • Uniprot No.：
    Q53FZ2
  • 基因名：
    ACSM3
  • 别名：
    ACSM3 antibody; ACSM3_HUMAN antibody; Acyl CoA synthetase medium chain family member 3 antibody; Acyl-CoA synthetase medium-chain family member 3 antibody; Acyl-coenzyme A synthetase ACSM3 antibody; Acyl-coenzyme A synthetase ACSM3; mitochondrial antibody; Butyrate CoA ligase 3 antibody; Butyrate--CoA ligase 3 antibody; Butyryl coenzyme A synthetase 3 antibody; Butyryl-coenzyme A synthetase 3 antibody; Middle chain acyl CoA synthetase 3 antibody; Middle-chain acyl-CoA synthetase 3 antibody; mitochondrial antibody; Protein SA homolog antibody; SA (rat hypertension associated) homolog antibody; SA antibody; SA hypertension associated homolog antibody; SA; rat; homolog of antibody; SAH antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Acyl-coenzyme A synthetase ACSM3, mitochondrial protein (387-586AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism. Capable of activating medium-chain fatty acids with a preference for isobutyrate among fatty acids with 2-6 carbon atoms.
  • 基因功能参考文献：
    1. Our data provide evidence for a differential expression and regulation of the ACSM3 gene in hepatocellular carcinoma PMID: 28390038
    2. Reduced ACSM3 is associated with impaired butyrate oxidation in ulcerative colitis. PMID: 21987487
    3. SA gene polymorphism may be associated with the renal prognosis of immunoglobulin A nephropathy through its effect on blood pressure. Sensitivity to this gene polymorphism increases in patients with renal injury. PMID: 12484505
    4. variation in SAH has a role in predisposition to overweight in hypertensives. PMID: 14567496
    5. confirms recent evidence that the SAH locus is associated with obesity-related hypertension PMID: 17278971
    6. family-based analyses of SA hypertension-associated homolog (SAH) gene variants did not reveal population stratification supporting an association of hypertension and gene variants PMID: 18192838
    7. We conclude that, in spite of its renal expression,1-3 the human SAH gene is unlikely to have an important role in renal sodium handling. PMID: 18519841
    8. SA hypertension-associated homolog(SAH) gene polymorphisms are associated with non-high-density lipoprotein cholesterol in postmenopausal women PMID: 19108963
    9. left ventricular mass index and mean wall thickness , two phenotypes that are jointly influenced by blood pressure and obesity, might be related to variation in the human SAH gene PMID: 19262474

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  • 亚细胞定位：
    Mitochondrion. Mitochondrion matrix.
  • 蛋白家族：
    ATP-dependent AMP-binding enzyme family
  • 数据库链接：

    HGNC: 10522

    OMIM: 145505

    KEGG: hsa:6296

    STRING: 9606.ENSP00000289416

    UniGene: Hs.706754