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ACSS1 Antibody

  • 货号：
    CSB-PA000808
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HT29 cells using ACSS1 Polyclonal Antibody
    • Western Blot analysis of HT29 cells using ACSS1 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9NUB1
  • 基因名：
    ACSS1
  • 别名：
    ACAS2L antibody; AceCS2 antibody; AceCS2L antibody; Acetate CoA ligase 2 antibody; Acetate--CoA ligase 2 antibody; Acetyl CoA synthetase 2 antibody; Acetyl Coenzyme A synthetase 2 (AMP forming) like antibody; Acetyl coenzyme A synthetase 2 like; mitochondrial antibody; Acetyl-CoA synthetase 2 antibody; Acetyl-coenzyme A synthetase 2-like; mitochondrial antibody; ACS2L_HUMAN antibody; Acss1 antibody; Acyl CoA synthetase short chain family member 1 antibody; Acyl-CoA synthetase short-chain family member 1 antibody; FLJ45659 antibody; KIAA1846 antibody; MGC33843 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human ACSS1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions. Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient.
  • 基因功能参考文献：
    1. citrate synthase and ACSS1 have tumorigenic functions in hepatocellular carcinoma PMID: 27363021
    2. ACSS1 is essential for glucose-independent acetate-mediated cell survival and tumor growth. PMID: 27539851
  • 亚细胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    ATP-dependent AMP-binding enzyme family
  • 数据库链接：

    HGNC: 16091

    OMIM: 614355

    KEGG: hsa:84532

    STRING: 9606.ENSP00000316924

    UniGene: Hs.529353