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ADSS Antibody

  • 货号：
    CSB-PA001398ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: Adenylosuccinate synthetase isozyme 2 antibody at 12μg/ml
      Lane 1: Mouse skeletal muscle tissue
      Lane 2: HepG2 whole cell lysate
      Lane 3: K562 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 50 kDa
      Observed band size: 50 kDa
    • Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA001398ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA001398ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ADSS Polyclonal antibody
  • Uniprot No.：
    P30520
  • 基因名：
    ADSS
  • 别名：
    ADSS2 antibody; ADSS antibody; Adenylosuccinate synthetase isozyme 2 antibody; AMPSase 2 antibody; AdSS 2 antibody; EC 6.3.4.4 antibody; Adenylosuccinate synthetase antibody; acidic isozyme antibody; Adenylosuccinate synthetase antibody; liver isozyme antibody; L-type adenylosuccinate synthetase antibody; IMP--aspartate ligase 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Adenylosuccinate synthetase isozyme 2 protein (1-280AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
  • 基因功能参考文献：
    1. Kinetic data reveal that human Ser(289) and B. subtilis Ser(262) and Ser(263) are essential for catalysis, while the ability of these Ser mutants to bind APBADP suggests that they do not contribute to substrate affinity PMID: 18469177
    2. These findings suggest that the combined effects of the polymorphisms in the ADSS and ATM genes may confer susceptibility to the development of schizophrenia in a Chinese population PMID: 19115993
  • 亚细胞定位：
    Cytoplasm. Mitochondrion. Note=Partially associated with particulate fractions.
  • 蛋白家族：
    Adenylosuccinate synthetase family
  • 数据库链接：

    HGNC: 292

    OMIM: 103060

    KEGG: hsa:159

    STRING: 9606.ENSP00000355493

    UniGene: Hs.498313