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AGBL3 Antibody

  • 货号：
    CSB-PA017539
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA017539(AGBL3 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8+12%SDS-PAGE, Lysate: 40 μg, Lane: Mouse pancreas tissue, Primary antibody: CSB-PA017539(AGBL3 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

产品详情

  • Uniprot No.：
    Q8NEM8
  • 基因名：
    AGBL3
  • 别名：
    CCP3 antibody; Agbl3 antibody; ATP/GTP-binding protein-like 3 antibody; CBPC3_HUMAN antibody; Cytosolic carboxypeptidase 3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human AGBL3
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK. May catalyze the hydrolysis of aspartate from the carboxy-terminus of target proteins. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of target proteins.; Metallocarboxypeptidase that mediates tubulin deglutamylation.
  • 基因功能参考文献：
    1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    Peptidase M14 family
  • 数据库链接：

    HGNC: 27981

    OMIM: 617346

    KEGG: hsa:340351

    STRING: 9606.ENSP00000388275

    UniGene: Hs.648616