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AK6 Antibody

  • 中文名称：
    AK6多克隆抗体
  • 货号：
    CSB-PA000841
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of Jurkat cells using AK6 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9Y3D8
  • 基因名：
    AK6
  • 别名：
    AD-004 antibody; Adenylate kinase isoenzyme 6 antibody; Adrenal gland protein AD-004 antibody; AK/ATPase antibody; AK6 antibody; CGI-137 antibody; CIP antibody; Coilin-interacting nuclear ATPase protein antibody; Dual activity adenylate kinase/ATPase antibody; hCINAP antibody; KAD6_HUMAN antibody; TAF9 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human AK6.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. AMP and dAMP are the preferred substrates, but CMP and dCMP are also good substrates. IMP is phosphorylated to a much lesser extent. All nucleoside triphosphates ATP, GTP, UTP, CTP, dATP, dCTP, dGTP, and TTP are accepted as phosphate donors. CTP is the best phosphate donor, followed by UTP, ATP, GTP and dCTP. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
  • 基因功能参考文献：
    1. hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation. PMID: 28516914
    2. purification and X ray crystal structure PMID: 15213396
    3. hCINAP is a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus PMID: 16079131
  • 亚细胞定位：
    Nucleus, nucleoplasm. Nucleus, Cajal body. Note=Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells.
  • 蛋白家族：
    Adenylate kinase family, AK6 subfamily
  • 组织特异性：
    Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, chorionic villi and the central nervous system.
  • 数据库链接：

    HGNC: 49151

    KEGG: hsa:102157402

    UniGene: Hs.653163