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AKR7A3 Antibody

  • 货号：
    CSB-PA001551ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA001551ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA001551ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) AKR7A3 Polyclonal antibody
  • Uniprot No.：
    O95154
  • 基因名：
    AKR7A3
  • 别名：
    AFAR 2 antibody; AFAR2 antibody; AFB1 aldehyde reductase 2 antibody; AFB1 AR 2 antibody; AFB1-AR 2 antibody; Aflatoxin aldehyde reductase antibody; Aflatoxin B1 aldehyde reductase 2 antibody; Aflatoxin B1 aldehyde reductase member 3 antibody; Akr7a3 antibody; Aldo keto reductase family 7 member A3 antibody; ARK73_HUMAN antibody; OTTHUMP00000002623 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Aflatoxin B1 aldehyde reductase member 3 protein (1-331AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
  • 基因功能参考文献：
    1. Results demonstrate that Akr7a3 mRNA and protein levels are consistently co-expressed along with Akr1b10, in both experimental rat liver carcinogenesis and some human hepatocellular carcinoma samples. PMID: 29383608
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Aldo/keto reductase family, Aldo/keto reductase 2 subfamily
  • 组织特异性：
    Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium.
  • 数据库链接：

    HGNC: 390

    OMIM: 608477

    KEGG: hsa:22977

    STRING: 9606.ENSP00000355377

    UniGene: Hs.6980