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ALDH6A1 Antibody

  • 货号：
    CSB-PA280938
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA280938(ALDH6A1 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA280938(ALDH6A1 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Rat kidney tissue, human fetal kidney tissue, Jurkat cells, K562 cells, Primary antibody: CSB-PA280938(ALDH6A1 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

产品详情

  • Uniprot No.：
    Q02252
  • 基因名：
    ALDH6A1
  • 别名：
    1110038I05Rik antibody; AI314632 antibody; Aldehyde dehydrogenase 6 family member A1 antibody; Aldehyde dehydrogenase family 6 member A1 antibody; Aldehyde dehydrogenase family 6, subfamily A1 antibody; ALDH6A1 antibody; Malonate semialdehyde dehydrogenase antibody; Malonate-semialdehyde dehydrogenase [acylating] antibody; Methylmalonate semialdehyde dehydrogenase [acylating] mitochondrial antibody; Methylmalonate-semialdehyde dehydrogenase [acylating] antibody; MGC37325 antibody; MGC40271 antibody; Mitochondrial acylating methylmalonate semialdehyde dehydrogenase antibody; mitochondrial antibody; MMSA_HUMAN antibody; MMSADHA antibody; MMSDH antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human ALDH6A1
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:200-1:1000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
  • 基因功能参考文献：
    1. Results show that ALDH6A1 expression is significantly reduced in metastatic prostate cancer and represents a strong marker predicting survival, along with HSP27 and prohibitin. PMID: 30396985
    2. ACAT1, ACACA, ALDH6A1 and MTHFD1 represent novel biomarkers in adipose tissue associated with type 2 diabetes in obese individuals. PMID: 25099943
    3. Mutation analysis in the ALDH6A1 gene can reveal a cause of 3-hydroxyisobutyric aciduria, which may present with only slightly increased urinary levels of 3-hydroxyisobutyric acid, if a patient is metabolically stable [case reports] PMID: 21863277
  • 相关疾病：
    Methylmalonate semialdehyde dehydrogenase deficiency (MMSDHD)
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    Aldehyde dehydrogenase family
  • 数据库链接：

    HGNC: 7179

    OMIM: 603178

    KEGG: hsa:4329

    STRING: 9606.ENSP00000450436

    UniGene: Hs.293970