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ALG2 Antibody

  • 货号：
    CSB-PA314311
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA314311(ALG2 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA314311(ALG2 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q9H553
  • 基因名：
    ALG2
  • 别名：
    ALG2; UNQ666/PRO1298; Alpha-1,3/1,6-mannosyltransferase ALG2; Asparagine-linked glycosylation protein 2 homolog; GDP-Man:Man(1GlcNAc(2-PP-Dol alpha-1,3-mannosyltransferase; GDP-Man:Man(1GlcNAc(2-PP-dolichol mannosyltransferase; GDP-Man:Man(2GlcNAc(2-PP-Dol alpha-1,6-mannosyltransferase
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human ALG2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
  • 基因功能参考文献：
    1. We identify ALG14 and ALG2 as novel genes in which mutations cause a congenital myasthenic syndrome PMID: 23404334
    2. The ALG2 binding site is necessary for the punctate distribution of the carboxyl-terminal proline-rich region of Alix in HeLa cells. PMID: 14999017
    3. The expression and transport of ALG-2 in association with TSG101 and Vps4B are reported. PMID: 16004603
  • 相关疾病：
    Congenital disorder of glycosylation 1I (CDG1I); Myasthenic syndrome, congenital, 14 (CMS14)
  • 亚细胞定位：
    Membrane; Single-pass membrane protein.
  • 蛋白家族：
    Glycosyltransferase group 1 family, Glycosyltransferase 4 subfamily
  • 数据库链接：

    HGNC: 23159

    OMIM: 607905

    KEGG: hsa:85365

    STRING: 9606.ENSP00000417764

    UniGene: Hs.40919