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ANAPC4 Antibody

  • 货号:
    CSB-PA001699GA01HU
  • 规格:
    ¥3,900
  • 其他:

产品详情

  • Uniprot No.:
    Q9UJX5
  • 基因名:
  • 别名:
    ANAPC 4 antibody; anapc4 antibody; Anaphase Promoting Complex Subunit 4 antibody; Anaphase-promoting complex subunit 4 antibody; APC 4 antibody; APC Complex Protein CUT20 antibody; APC4 antibody; APC4_HUMAN antibody; CUT20 antibody; Cyclosome subunit 4 antibody; LID1 antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human,Mouse,Rat
  • 免疫原:
    Human ANAPC4
  • 免疫原种属:
    Homo sapiens (Human)
  • 抗体亚型:
    IgG
  • 纯化方式:
    Antigen Affinity purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA,WB,IHC
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
  • 基因功能参考文献:
    1. Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated phosphorylation of Cdh1. PMID: 20686030
    2. Studies indicate that APC/C(Cdh1) is required to maintain genomic stability. PMID: 19826416
  • 亚细胞定位:
    Nucleus.
  • 蛋白家族:
    APC4 family
  • 数据库链接:

    HGNC: 19990

    OMIM: 606947

    KEGG: hsa:29945

    STRING: 9606.ENSP00000318775

    UniGene: Hs.152173