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AP1S1 Antibody

  • 货号：
    CSB-PA001866LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) AP1S1 Polyclonal antibody
  • Uniprot No.：
    P61966
  • 基因名：
    AP1S1
  • 别名：
    Adapter related protein complex 1 sigma 1A subunit antibody; Adapter-related protein complex 1 sigma-1A subunit antibody; Adaptor protein complex AP-1 sigma-1A subunit antibody; Adaptor protein complex AP1 sigma 1A subunit antibody; AP-1 complex subunit sigma-1A antibody; AP1 complex subunit sigma 1A antibody; AP19 antibody; AP1S1 antibody; AP1S1_HUMAN antibody; CLAPS1 antibody; Clathrin assembly protein complex 1 sigma 1A small chain antibody; Clathrin assembly protein complex 1 sigma-1A small chain antibody; Clathrin coat assembly protein AP19 antibody; Golgi adaptor HA1/AP1 adaptin sigma 1A subunit antibody; Golgi adaptor HA1/AP1 adaptin sigma-1A subunit antibody; HA1 19 kDa subunit antibody; Sigma 1a subunit of AP-1 clathrin antibody; Sigma 1a subunit of AP1 clathrin antibody; Sigma adaptin 1A antibody; Sigma-adaptin 1A antibody; Sigma1A adaptin antibody; Sigma1A-adaptin antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human AP-1 complex subunit sigma-1A protein (1-127AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，AP1S1 Antibody (CSB-PA001866LA01HU)，的标记方式是Non-conjugated。对于AP1S1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA001866LB01HU AP1S1 Antibody, HRP conjugated ELISA
    FITC CSB-PA001866LC01HU AP1S1 Antibody, FITC conjugated
    Biotin CSB-PA001866LD01HU AP1S1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
  • 基因功能参考文献：
    1. We solved the pathogenetic mechanism of MEDNIK syndrome, demonstrating that AP1S1 regulates intracellular copper machinery mediated by copper-pump proteins PMID: 23423674
    2. A splice mutation in AP1S1 was found in four families with a neurocutaneous syndrome. PMID: 19057675
    3. Isolation and description of the rat and mouse genes. PMID: 2040623
  • 相关疾病：
    Mental retardation, enteropathy, deafness, peripheral neuropathy, ichthyosis, and keratoderma (MEDNIK)
  • 亚细胞定位：
    Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
  • 蛋白家族：
    Adaptor complexes small subunit family
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 559

    OMIM: 603531

    KEGG: hsa:1174

    STRING: 9606.ENSP00000336666

    UniGene: Hs.489365