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APOBEC3A Antibody

  • 货号：
    CSB-PA001921LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) APOBEC3A Polyclonal antibody
  • Uniprot No.：
    P31941
  • 基因名：
    APOBEC3A
  • 别名：
    A3A antibody; ABC3A_HUMAN antibody; APOBEC3A antibody; Apolipoprotein B mRNA editing enzyme antibody; Apolipoprotein B mRNA editing enzyme; catalytic polypeptide like 3A antibody; ARP3 antibody; bK150C2.1 antibody; Catalytic polypeptide like 3A antibody; Phorbolin 1 antibody; Phorbolin-1 antibody; PHRBN antibody; Probable DNA dC >dU editing enzyme APOBEC-3A antibody; Probable DNA dC->dU-editing enzyme APOBEC-3A antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human DNA dC->dU-editing enzyme APOBEC-3A protein (1-199AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，APOBEC3A Antibody (CSB-PA001921LA01HU)，的标记方式是Non-conjugated。对于APOBEC3A Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA001921LB01HU APOBEC3A Antibody, HRP conjugated ELISA
    FITC CSB-PA001921LC01HU APOBEC3A Antibody, FITC conjugated
    Biotin CSB-PA001921LD01HU APOBEC3A Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
  • 基因功能参考文献：
    1. the APOBEC3A/B deletion polymorphism was not associated with risk of breast, lung, colon or prostate cancer in this Norwegian cohort PMID: 29140415
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    Cytidine and deoxycytidylate deaminase family
  • 组织特异性：
    Expressed in peripheral leukocytes with higher expression in CD14-positive phagocytic cells. Highly expressed in keratinocytes and in periphery blood monocytes. Also detected in non-lymphoid tissues including lung and adipose tissues. Found at high levels
  • 数据库链接：

    HGNC: 17343

    OMIM: 607109

    KEGG: hsa:100913187

    STRING: 9606.ENSP00000249116

    UniGene: Hs.226307