APOBEC3D Antibody
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货号:CSB-PA846585LA01HU
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规格:¥440
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促销:
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图片:
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Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA846585LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA846585LA01HU at dilution of 1:100
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Immunofluorescence staining of Hela cells with CSB-PA846585LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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其他:
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) APOBEC3D Polyclonal antibody
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Uniprot No.:Q96AK3
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基因名:APOBEC3D
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别名:A3D antibody; ABC3D_HUMAN antibody; APOBEC3D antibody; APOBEC3DE antibody; APOBEC3E antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3D antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3E pseudogene antibody; ARP6 antibody; bK150C2.9 antibody; BK150C2.9 protein antibody; DNA dC >dU editing enzyme APOBEC 3D antibody; DNA dC->dU-editing enzyme APOBEC-3D antibody; hCG_41704 antibody; HCG41704; isoform CRA_b antibody; Probable DNA dC->dU-editing enzyme APOBEC-3D antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human DNA dC->dU-editing enzyme APOBEC-3D protein (250-371AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
本页面中的产品,APOBEC3D Antibody (CSB-PA846585LA01HU),的标记方式是Non-conjugated。对于APOBEC3D Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA, IHC, IF
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推荐稀释比:
Application Recommended Dilution IHC 1:20-1:200 IF 1:50-1:200 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against Vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons.
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亚细胞定位:Cytoplasm. Cytoplasm, P-body.
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蛋白家族:Cytidine and deoxycytidylate deaminase family
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组织特异性:Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung.
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数据库链接:
HGNC: 17354
OMIM: 609900
STRING: 9606.ENSP00000216099
UniGene: Hs.629775
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