ARF3 Antibody
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货号:CSB-PA001990GA01HU
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规格:¥3,900
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其他:
产品详情
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Uniprot No.:P61204
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基因名:
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别名:ADP ribosylation factor 3 antibody; ADP-ribosylation factor 3 antibody; ARF3 antibody; ARF3_HUMAN antibody; small GTP binding protein antibody
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宿主:Rabbit
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反应种属:Human,Mouse,Rat
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免疫原:Human ARF3
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免疫原种属:Homo sapiens (Human)
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抗体亚型:IgG
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纯化方式:Antigen Affinity Purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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产品提供形式:Liquid
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应用范围:ELISA,WB,IHC
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
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基因功能参考文献:
- Upregulation of ARF3 is associated with ovarian cancer. PMID: 28098897
- activated ARF3 is associated with Unc93B1 and TLR9, suggesting that ARF3 conducts TLR9 trafficking by forming the TLR9-Unc93B1-ARF3 complex. PMID: 26067373
- ARF1+ARF3 are required for integrity of recycling endosomes but are involved in distinct transport pathways: they are required for the transferrin recycling pathway from endosomes to the plasma membrane. PMID: 23783033
- These results suggest that Arf3 plays a unique function at the trans-Golgi network that likely involves recruitment by a specific receptor. PMID: 20357002
- expression and subcellular redistribution by heregulin PMID: 12135740
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亚细胞定位:Golgi apparatus. Cytoplasm, perinuclear region.
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蛋白家族:Small GTPase superfamily, Arf family
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数据库链接:
HGNC: 654
OMIM: 103190
KEGG: hsa:377
STRING: 9606.ENSP00000256682
UniGene: Hs.119177
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